Immunohistochemistry (IHC)
(Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit FLG/Filaggrin Polyclonal Antibody | anti-FLG antibody
Anti-FLG/Filaggrin Antibody
Gene Names
FLG; ATOD2
Reactivity
HumanPredicted: Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
FLG/Filaggrin; Polyclonal Antibody; Anti-FLG/Filaggrin Antibody; Mouse Monoclonal [clone FLG01] (IgG1; k) to Human FLG/Filaggrin; FLG; ATOD2; Epidermal filaggrin; Filaggrin; anti-FLG antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Specificity
Human FLG/Filaggrin
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.2, 0.05% sodium azide.
Sequence Length
4061
Applicable Applications for anti-FLG antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:200
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human Filaggrin.
Conjugation
Unconjugated
Preparation and Storage
Store at 4 degree C for short term.
Aliquot and store at -20 degree C for long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C for long term.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot (WB) analysis of Filaggrin pAb at 1:500 dilution. Lane1:Hela cell lysate. Lane2:sp2/0 cell lysate. Lane3:PC12 cell lysate.)
Western Blot (WB)
(Western blot (WB) analysis of Filaggrin pAb at 1:500 dilution. Lane1:Hela cell lysate. Lane2:sp2/0 cell lysate. Lane3:PC12 cell lysate.)
Related Product Information for anti-FLG antibody
FLG/Filaggrin is an intermediate filament-associated protein thataggregates keratin intermediate filaments in mammalian epidermis. It isinitially synthesized as a polyprotein precursor, profilaggrin(consisting of multiple filaggrin units of 324 aa each), which islocalized in keratohyalin granules, and is subsequently proteolyticallyprocessed into individual functional filaggrin molecules. Mutations inthis gene are associated with ichthyosis vulgaris.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
435,170 Da
NCBI Official Full Name
filaggrin
NCBI Official Synonym Full Names
filaggrin
NCBI Official Symbol
FLG
NCBI Official Synonym Symbols
ATOD2
NCBI Protein Information
filaggrin
UniProt Protein Name
Filaggrin
Protein Family
UniProt Gene Name
FLG
NCBI Description
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]
Uniprot Description
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Research Articles on FLG
Similar Products
Product Notes
The FLG flg (Catalog #AAA2401576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FLG/Filaggrin Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FLG/Filaggrin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:200 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the FLG flg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLG/Filaggrin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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