Western Blot (WB)
(Western blot analysis of FKBP10 Antibody (C-term) in A2058 and A375 cell line lysates (35ug/lane). FKBP10 (arrow) was detected using the purified Pab.)
Rabbit anti-Human FKBP10 Polyclonal Antibody | anti-FKBP10 antibody
FKBP10 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of FKBP10 Antibody (C-term) in A2058 and A375 cell line lysates (35ug/lane). FKBP10 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of FKBP10 Antibody (C-term) in A2058 and A375 cell line lysates (35ug/lane). FKBP10 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(FKBP10 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FKBP10 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(FKBP10 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FKBP10 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(FKBP10 Antibody (C-term) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(FKBP10 Antibody (C-term) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Foster,L.J., J. Proteome Res. 5 (1), 64-75 (2006)
Zhang,H., Nat. Biotechnol. 21 (6), 660-666 (2003)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
Uniprot Description
FKBP10: PPIases accelerate the folding of proteins during protein synthesis. Defects in FKBP10 are the cause of osteogenesis imperfecta type 6 (OI6). OI6 is a moderate to severe, autosomal recessive form of osteogenesis imperfecta characterized by increased serum alkaline phosphatase levels and bone histology exhibiting a fish scale-like lamellar pattern. Osteogenesis imperfecta defines a group of connective tissue disorders characterized by bone fragility and low bone mass.
Protein type: Isomerase; EC 5.2.1.8
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum lumen
Molecular Function: peptidyl-prolyl cis-trans isomerase activity; FK506 binding; calcium ion binding
Biological Process: protein peptidyl-prolyl isomerization
Disease: Osteogenesis Imperfecta, Type Xi; Bruck Syndrome 1
Research Articles on FKBP10
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Product Notes
The FKBP10 fkbp10 (Catalog #AAA9211168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 552-580. The FKBP10 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FKBP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the FKBP10 fkbp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FKBP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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