Western Blot (WB)
(Western Blot: Sample: Mouse Heart lysate; Primary Ab: 3ug/ml Rabbit Anti-Human FRS2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2) Polyclonal Antibody | anti-FRS2 antibody
Polyclonal Antibody to Fibroblast Growth Factor Receptor Substrate 2 (FRS2)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- DP QILLEPEGVK FVLGPTPVQK QLMEKEKLEQ LGRDQVSGSG ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST SDTQNINNSA QRRTALLNYE NLPSLPPVWE ARKLSRDEDD NLGPKTPSLN GYHNNLDPMH NYVNTENVTV PASAHKIEYS RRRDCTPTVF NFDIRRPSLE HRQLNYIQVD LEGGSDSDN
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Mouse Heart lysate; Primary Ab: 3ug/ml Rabbit Anti-Human FRS2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Mouse Heart lysate; Primary Ab: 3ug/ml Rabbit Anti-Human FRS2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
NCBI and Uniprot Product Information
Uniprot Description
FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: cell-cell adherens junction; endosome; integral component of plasma membrane; membrane; plasma membrane
Molecular Function: 1-phosphatidylinositol-3-kinase activity; fibroblast growth factor receptor binding; insulin receptor binding; neurotrophin TRKA receptor binding; phosphatase activator activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; Ras guanyl-nucleotide exchange factor activity; transmembrane receptor protein tyrosine kinase adaptor protein activity
Biological Process: activation of MAPK activity; activation of MAPKK activity; anterior/posterior axis specification, embryo; axon guidance; fibroblast growth factor receptor signaling pathway; forebrain development; G-protein coupled receptor signaling pathway; gastrulation with mouth forming second; induction of an organ; lens fiber cell development; MAPK cascade; negative regulation of cardiac muscle cell differentiation; neuroblast proliferation; optic placode formation involved in camera-type eye formation; phosphatidylinositol phosphorylation; positive regulation of protein kinase B signaling; regulation of apoptosis; regulation of epithelial cell proliferation; regulation of ERK1 and ERK2 cascade; transmembrane receptor protein tyrosine phosphatase signaling pathway; ventricular septum development
Research Articles on FRS2
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Product Notes
The FRS2 frs2 (Catalog #AAA2004990) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Fibroblast Growth Factor Receptor Substrate 2 (FRS2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Fibroblast Growth Factor Receptor Substrate 2 (FRS2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the FRS2 frs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- DP QILLEPEGVK FVLGPTPVQK QLMEKEKLEQ LGRDQVSGSG ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST SDTQNINNSA QRRTALLNYE NLPSLPPVWE ARKLSRDEDD NLGPKTPSLN GYHNNLDPMH NYVNTENVTV PASAHKIEYS RRRDCTPTVF NFDIRRPSLE HRQLNYIQVD LEGGSDSDN. It is sometimes possible for the material contained within the vial of "Fibroblast Growth Factor Receptor Substrate 2 (FRS2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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