Western Blot (WB)
(Western Blot: Sample: Recombinant FGFRL1, Human.)
Rabbit anti-Human Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Polyclonal Antibody | anti-FGFRL1 antibody
Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- VRL KCVASGHPRP DITWMKDDQA LTRPEAAEPR KKKWTLSLKN LRPEDSGKYT CRVSNRAGAI NATYKVDVIQ RTRSKPVLTG THPVNTTVDF GGTTSFQCKV RSDVKPVIQW LKRVEYGAEG RHNSTIDVGG QKFVVLPTGD VWSRPDGSYL NKLLITRARQ DDAGMYICLG ANTMGYSFRS AFLTVLPDPK PPGPPVASSS SATSLPWP
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant FGFRL1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant FGFRL1, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Pancreas Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Pancreas Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Lung Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Lung Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
FGFRL1: Has a negative effect on cell proliferation.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: Golgi apparatus; integral component of membrane; plasma membrane; transport vesicle
Molecular Function: fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; heparin binding
Biological Process: fibroblast growth factor receptor signaling pathway; negative regulation of cell proliferation; protein heterooligomerization; protein homooligomerization; skeletal system development
Disease: Wolf-hirschhorn Syndrome
Research Articles on FGFRL1
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Product Notes
The FGFRL1 fgfrl1 (Catalog #AAA2006046) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the FGFRL1 fgfrl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- VRL KCVASGHPRP DITWMKDDQA LTRPEAAEPR KKKWTLSLKN LRPEDSGKYT CRVSNRAGAI NATYKVDVIQ RTRSKPVLTG THPVNTTVDF GGTTSFQCKV RSDVKPVIQW LKRVEYGAEG RHNSTIDVGG QKFVVLPTGD VWSRPDGSYL NKLLITRARQ DDAGMYICLG ANTMGYSFRS AFLTVLPDPK PPGPPVASSS SATSLPWP. It is sometimes possible for the material contained within the vial of "Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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