Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using FGFBP1 antibody.)
Rabbit FGFBP1 Polyclonal Antibody | anti-FGFBP1 antibody
FGFBP1 Polyclonal Antibody
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using FGFBP1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using FGFBP1 antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
Uniprot Description
FGFBP1: Acts as a carrier protein that release fibroblast- binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. Belongs to the fibroblast growth factor-binding protein family.
Chromosomal Location of Human Ortholog: 4p15.32
Cellular Component: cell surface; extracellular region; extracellular space; plasma membrane
Molecular Function: fibroblast growth factor binding; heparin binding; protein binding
Biological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; negative regulation of cell proliferation; positive regulation of cell proliferation; positive regulation of defense response to virus by host; positive regulation of fibroblast growth factor receptor signaling pathway; signal transduction
Research Articles on FGFBP1
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Product Notes
The FGFBP1 fgfbp1 (Catalog #AAA2536544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FGFBP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FGFBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000, IHC: 1:50-1:200. Researchers should empirically determine the suitability of the FGFBP1 fgfbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGFBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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