Rabbit anti-Mouse, Rat Fgf19(Fgf15) Polyclonal Antibody | anti-Fgf19(Fgf15) antibody
Anti-Fgf19(Fgf15) Antibody
Gene Names
Fgf19; Fgf15
Reactivity
Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
Purity
Immunogen affinity purified.
Synonyms
Fgf19(Fgf15); Polyclonal Antibody; Anti-Fgf19(Fgf15) Antibody; Fgf15; Fibroblast growth factor 15; FGF-15; Fibroblast growth factor; FGF; Fgf19; FGF15; rCG_47906; fibroblast growth factor 19(fibroblast growth factor 15); anti-Fgf19(Fgf15) antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Rabbit IgG polyclonal antibody for Fgf19(Fgf15) detection.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized. Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.
Applicable Applications for anti-Fgf19(Fgf15) antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS/FCM), Direct ELISA (EIA)
Application Notes
WB: 0.25-0.5ug/ml|Mouse, Rat|
ICC/IF: 5ug/ml|Rat|
FC/FACS/FCM: 1-3ug/1x106 cells|Mouse, Rat|
Direct ELISA: 0.1-0.5ug/ml|Rat|
ICC/IF: 5ug/ml|Rat|
FC/FACS/FCM: 1-3ug/1x106 cells|Mouse, Rat|
Direct ELISA: 0.1-0.5ug/ml|Rat|
Immunogen
E Coli-derived rat Fgf19(Fgf15) recombinant protein (Position: R26-K218).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Recommended Detection Systems
Recommended Detection Systems
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Related Product Information for anti-Fgf19(Fgf15) antibody
FGF15/19 refers to two orthologous fibroblast growth factors which share 50% aminoacid identity and have similar functions. FGF15 was described in the mouse; FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They were first described in developing fetal brain. They are now known to be produced in the ileum, and under certain circumstances in the liver and biliary tree. It is thought their principal function is in response to bile acid absorption occurring after meals. FGF15 and FGF19 have similar roles in regulating bile acid synthesis and also glucose metabolism in the liver.
References
1. Jones, SA (2012). "Physiology of FGF15/19". Advances in Experimental Medicine and Biology. 728: 171-82.
2. Potthoff, MJ; Kliewer, SA; Mangelsdorf, DJ (2012). "Endocrine fibroblast growth factors 15/19 and 21: from feast to famine". Genes & Development. 26 (4): 312-324.
3. Owen, BM; Mangelsdorf, DJ; Kliewer, SA (January 2015). "Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21". Trends in Endocrinology and Metabolism. 26 (1): 22-9.
2. Potthoff, MJ; Kliewer, SA; Mangelsdorf, DJ (2012). "Endocrine fibroblast growth factors 15/19 and 21: from feast to famine". Genes & Development. 26 (4): 312-324.
3. Owen, BM; Mangelsdorf, DJ; Kliewer, SA (January 2015). "Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21". Trends in Endocrinology and Metabolism. 26 (1): 22-9.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,207 Da
NCBI Official Full Name
fibroblast growth factor 19
NCBI Official Synonym Full Names
fibroblast growth factor 19
NCBI Official Symbol
Fgf19
NCBI Official Synonym Symbols
Fgf15
NCBI Protein Information
fibroblast growth factor 19
UniProt Protein Name
Fibroblast growth factor 15
UniProt Gene Name
Fgf19
NCBI Description
member of the fibroblast growth factor (FGF) family; implicated in activities including embryonic development, cell growth, morphogenesis, tissue growth, and tumor growth and invasion [RGD, Feb 2006]
Research Articles on Fgf19(Fgf15)
Similar Products
Product Notes
The Fgf19(Fgf15) fgf19 (Catalog #AAA1753406) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Fgf19(Fgf15) Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Fgf19(Fgf15) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS/FCM), Direct ELISA (EIA). WB: 0.25-0.5ug/ml|Mouse, Rat| ICC/IF: 5ug/ml|Rat| FC/FACS/FCM: 1-3ug/1x106 cells|Mouse, Rat| Direct ELISA: 0.1-0.5ug/ml|Rat|. Researchers should empirically determine the suitability of the Fgf19(Fgf15) fgf19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fgf19(Fgf15), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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