Western Blot (WB)
(FERMT2 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FERMT2 antibody detected the FERMT2 protein (arrow).)
Rabbit anti-Human FERMT2 Polyclonal Antibody | anti-FERMT2 antibody
FERMT2, CT (FERMT2, KIND2, MIG2, PLEKHC1, Fermitin family homolog 2, Kindlin-2, Mitogen-inducible gene 2 protein, Pleckstrin homology domain-containing family C member 1)
Gene Names
FERMT2; MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
FERMT2; Polyclonal Antibody; CT (FERMT2; KIND2; MIG2; PLEKHC1; Fermitin family homolog 2; Kindlin-2; Mitogen-inducible gene 2 protein; Pleckstrin homology domain-containing family C member 1); Anti -FERMT2; anti-FERMT2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-FERMT2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
FERMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 641-669 amino acids from the C-terminal region of human FERMT2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(FERMT2 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FERMT2 antibody detected the FERMT2 protein (arrow).)
Western Blot (WB)
(FERMT2 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FERMT2 antibody detected the FERMT2 protein (arrow).)
Related Product Information for anti-FERMT2 antibody
FERMT2 participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
Product Categories/Family for anti-FERMT2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77,861 Da
NCBI Official Full Name
fermitin family homolog 2 isoform 3
NCBI Official Synonym Full Names
fermitin family member 2
NCBI Official Symbol
FERMT2
NCBI Official Synonym Symbols
MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B
NCBI Protein Information
fermitin family homolog 2; kindlin 2; kindlin-2; mitogen inducible gene 2 protein; mitogen-inducible gene 2 protein; PH domain-containing family C member 1; pleckstrin homology domain-containing family C member 1; pleckstrin homology domain containing, family C member 1; pleckstrin homology domain containing, family C (with FERM domain) member 1
UniProt Protein Name
Fermitin family homolog 2
Protein Family
UniProt Gene Name
FERMT2
UniProt Synonym Gene Names
KIND2; MIG2; PLEKHC1; MIG-2
UniProt Entry Name
FERM2_HUMAN
Uniprot Description
Kindlin-2: Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Belongs to the kindlin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 14q22.1
Cellular Component: nucleoplasm; I band; filamentous actin; extrinsic to internal side of plasma membrane; focal adhesion; cell surface; cytoplasm; stress fiber; cell cortex; nucleus; cytosol
Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding
Biological Process: focal adhesion formation; integrin activation; integrin-mediated signaling pathway; regulation of cell shape; Wnt receptor signaling pathway; cell-matrix adhesion; transforming growth factor beta receptor signaling pathway
Research Articles on FERMT2
Similar Products
Product Notes
The FERMT2 fermt2 (Catalog #AAA6010136) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FERMT2, CT (FERMT2, KIND2, MIG2, PLEKHC1, Fermitin family homolog 2, Kindlin-2, Mitogen-inducible gene 2 protein, Pleckstrin homology domain-containing family C member 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FERMT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the FERMT2 fermt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FERMT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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