Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Rabbit anti-Human FEM1A Polyclonal Antibody | anti-FEM1A antibody
FEM1A Antibody
Gene Names
FEM1A; EPRAP
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
FEM1A; Polyclonal Antibody; FEM1A Antibody; EPRAP; anti-FEM1A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total FEM1A protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.1 mg/ml (varies by lot)
Sequence Length
669
Applicable Applications for anti-FEM1A antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human fem-1 homolog a (C. elegans)
Target Name
FEM1A
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/20.)
Related Product Information for anti-FEM1A antibody
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
Product Categories/Family for anti-FEM1A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
73,639 Da
NCBI Official Full Name
protein fem-1 homolog A
NCBI Official Synonym Full Names
fem-1 homolog a (C. elegans)
NCBI Official Symbol
FEM1A
NCBI Official Synonym Symbols
EPRAP
NCBI Protein Information
protein fem-1 homolog A
UniProt Protein Name
Protein fem-1 homolog A
Protein Family
UniProt Gene Name
FEM1A
UniProt Synonym Gene Names
EPRAP; FEM1a
UniProt Entry Name
FEM1A_HUMAN
Uniprot Description
FEM1A: Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Belongs to the fem-1 family.
Protein type: Ubiquitin conjugating system; Ligase
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasm
Molecular Function: EP4 subtype prostaglandin E2 receptor binding; ubiquitin-protein ligase activity
Biological Process: regulation of ubiquitin-protein ligase activity; negative regulation of inflammatory response; protein ubiquitination
Research Articles on FEM1A
Similar Products
Product Notes
The FEM1A fem1a (Catalog #AAA9407517) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FEM1A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FEM1A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the FEM1A fem1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FEM1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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