Western Blot (WB)
(FCRLM2 polyclonal antibody. Western Blot analysis of FCRLM2 expression in human placenta.)
Mouse anti-Human FCRLB Polyclonal Antibody | anti-FCRLA antibody
FCRLB (Fc Receptor-like B, Fc Receptor Homolog Expressed in B-cells Protein 2, FREB-2, Fc Receptor-like and Mucin-like Protein 2, Fc Receptor-like Protein 2, Fc Receptor-related Protein Y, FcRY, FCRL2, FCRLM2, FCRY, FREB2, FLJ31052, RP11-474I16.6)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(FCRLM2 polyclonal antibody. Western Blot analysis of FCRLM2 expression in human placenta.)
Western Blot (WB)
(FCRLM2 polyclonal antibody. Western Blot analysis of FCRLM2 expression in human placenta.)
Western Blot (WB)
(FCRLB polyclonal antibody. Western Blot analysis of FCRLB expression in HeLa.)
Western Blot (WB)
(FCRLB polyclonal antibody. Western Blot analysis of FCRLB expression in HeLa.)
Western Blot (WB)
(Western Blot analysis of FCRLB expression in transfected 293T cell line by FCRLB polyclonal antibody. Lane1:FCRLM2 transfected lysate (34.32kD). Lane2:Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of FCRLB expression in transfected 293T cell line by FCRLB polyclonal antibody. Lane1:FCRLM2 transfected lysate (34.32kD). Lane2:Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
Function: May be implicated in B-cell differentiation and lymphomagenesis. Ref.1 Ref.2
Subunit structure: Monomer or homodimer; disulfide-linked.
Subcellular location: Secreted
Probable. Cytoplasm Ref.1 Ref.2 Ref.4.
Tissue specificity: Expressed specifically in primary and secondary lymphoid tissues like lymph node, spleen and tonsil. Specifically expressed in B-cells with a high level in normal germinal center B-cells, centroblasts and in a subset of diffuse large B-cell lymphomas. Highly expressed in bone marrow B-cells and weakly in earlier B lineage cells. Expressed in pre-germinal and germinal center B-cells in secondary lymphoid tissues. Also expressed in melanoma and melanocytes. Ref.1 Ref.2 Ref.3 Ref.4
Sequence similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Caution: It is uncertain whether Met-1 or Met-8 is the initiator.
Research Articles on FCRLA
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Product Notes
The FCRLA fcrla (Catalog #AAA647674) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FCRLB (Fc Receptor-like B, Fc Receptor Homolog Expressed in B-cells Protein 2, FREB-2, Fc Receptor-like and Mucin-like Protein 2, Fc Receptor-like Protein 2, Fc Receptor-related Protein Y, FcRY, FCRL2, FCRLM2, FCRY, FREB2, FLJ31052, RP11-474I16.6) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCRLB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the FCRLA fcrla for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MSIEKFWDRS SARKERAEVQ IAATWRVSLR LWTLSPLLCR EAALDPPPAW RLVPFPDAHP GFSLWLGTPT ERAALAGAGA TVGLGRRSDS LASCKAGAAS PILGCRTRAE CQSGCDMKRL AWSLFLSSFP RPSWTRSPCP TFQKAPLPPP RGHTASSPPP LVCGSARSPR GKQEGAGSRS GGQAGAVAPR PLRRAVPGAG AEGDGSAGGP RRGAGWGGAA LRHAPAPAEA RHAAAVRVLQ VQPRGAPLRL GRRVHSPGAR GRGARIVLVR GGYRHPQCPE TQSVAAAPGA RFSPGPGLHH RPSSMGRSLG SW. It is sometimes possible for the material contained within the vial of "FCRLB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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