Rabbit anti-Human FBXL18 Polyclonal Antibody | anti-FBXL18 antibody

FBXL18 (F-box and Leucine-rich Repeat Protein 18, F-box/LRR-repeat Protein 18, FBL18, FLJ10776, FLJ11467, FLJ26934, FLJ38075, FLJ41541)

Cat. Num. AAA6010277

• Gene Names: FBXL18; Fbl18
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: FBXL18; Polyclonal Antibody; FBXL18 (F-box and Leucine-rich Repeat Protein 18; F-box/LRR-repeat Protein 18; FBL18; FLJ10776; FLJ11467; FLJ26934; FLJ38075; FLJ41541); Anti -FBXL18 (F-box and Leucine-rich Repeat Protein 18; anti-FBXL18 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FBXL18.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MHAVPRGFGKKVRVGVQSCPPLLGPGVPPALLRVLVSAEEPALPGTPRADWVQLLLRHAPQRARHPQLAPTLQPRTECRGLGGGRHRPAGLPAAPDARTAAQRPYGLRAGQYRPAVPAVAVPVAGQPGHDGEGGVHARALRHVEALQAAEGPQAGAALLQRQRPVLPGAEPVPLAAAPVPGLSQRHPPARCRAGLHGSLPAGCHVPPVHRGVPRHLQEPAAVASPQLPGRAARVKRRHLPSAPRGPDRRHPGRPPGAPG

• Applicable Applications for anti-FBXL18 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human FBXL18, aa1-259 (AAH13435.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(FBXL18 rabbit polyclonal antibody. Western Blot analysis of FBXL18 expression in human liver.)

Western Blot (WB)

(FBXL18 rabbit polyclonal antibody. Western Blot analysis of FBXL18 expression in A-431.)

Western Blot (WB)

(Western Blot analysis of FBXL18 expression in transfected 293T cell line by FBXL18 polyclonal antibody. Lane 1: FBXL18 transfected lysate (26.9kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-FBXL18 antibody

Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40aa F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Product Categories/Family for anti-FBXL18 antibody

Antibodies; Abs to Ubiquitin Ligases

NCBI and Uniprot Product Information

• NCBI GI #: 19718810
• NCBI GeneID: 80028
• UniProt Accession #: Q96ME1; Q9BR90; Q9BTC7; Q9HAK7
• Molecular Weight: 88,341 Da
• NCBI Official Full Name: FBXL18 protein
• NCBI Official Synonym Full Names: F-box and leucine-rich repeat protein 18
• NCBI Official Symbol: FBXL18
• NCBI Official Synonym Symbols: Fbl18
• NCBI Protein Information: F-box/LRR-repeat protein 18
• UniProt Protein Name: F-box/LRR-repeat protein 18
• Protein Family: F-box/LRR-repeat protein
• UniProt Gene Name: FBXL18
• UniProt Synonym Gene Names: FBL18
• UniProt Entry Name: FXL18_HUMAN

NCBI Description

Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Uniprot Description

FBXL18: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 7p22.2