Rabbit anti-Human FBXL13 Polyclonal Antibody | anti-FBXL13 antibody

FBXL13, CT (FBXL13, FBL13, F-box/LRR-repeat protein 13, F-box and leucine-rich repeat protein 13) (PE)

Cat. Num. AAA6298240

• Gene Names: FBXL13; Fbl13
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FBXL13; Polyclonal Antibody; CT (FBXL13; FBL13; F-box/LRR-repeat protein 13; F-box and leucine-rich repeat protein 13) (PE); F-box and leucine-rich repeat protein 13; anti-FBXL13 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-FBXL13 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: FBXL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 682-710 amino acids from the C-terminal region of human FBXL13.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(FBXL13 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the FBXL13 antibody detected the FBXL13 protein (arrow).)

Related Product Information for anti-FBXL13 antibody

Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Product Categories/Family for anti-FBXL13 antibody

Antibodies; Ubiquitin Ligases

References

Rose, J. Phd, et al. Mol. Med. (2010). In press: Curtiss, N.P., et al. Genomics 85(5):600-607(2005). Jin, J., et al. Genes Dev. 18(21):2573-2580(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 161333854
• NCBI GeneID: 222235
• NCBI Accession #: NP_001104508.1; NP_659469.3
• NCBI GenBank Nucleotide #: NM_001111038.1
• UniProt Accession #: Q8NEE6; Q6UVW7; Q6UVW8; Q75MN5; Q86UJ5; Q8N7Y4; Q8TCL2; Q8WUF9; Q8WUG0; C9J565; C9J566
• Molecular Weight: 52,734 Da
• NCBI Official Full Name: F-box/LRR-repeat protein 13 isoform 2
• NCBI Official Synonym Full Names: F-box and leucine-rich repeat protein 13
• NCBI Official Symbol: FBXL13
• NCBI Official Synonym Symbols: Fbl13
• NCBI Protein Information: F-box/LRR-repeat protein 13
• UniProt Protein Name: F-box/LRR-repeat protein 13
• UniProt Gene Name: FBXL13
• UniProt Synonym Gene Names: FBL13
• UniProt Entry Name: FXL13_HUMAN

NCBI Description

Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Uniprot Description

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.