Rabbit anti-Human, Mouse FAM83H Polyclonal Antibody | anti-FAM83H antibody
FAM83H Antibody
Gene Names
FAM83H; AI3
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
FAM83H; Polyclonal Antibody; FAM83H Antibody; AI3; FA83H_HUMAN; Fam83h; Family with sequence similarity 83 member H; Protein FAM83H; anti-FAM83H antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
FAM83H Antibody detects endogenous levels of FAM83H.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-FAM83H antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human FAM83H.
Conjugation
Unconjugated
Similarity
Belongs to the FAM83 family.
Subunit Structure
Interacts with CSNK1A1; recruits CSNK1A1 to keratin filaments. Interacts with KRT18 and probably other keratins.
Tissue Specificity
Expressed in the tooth follicle.
Function
May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration.
Note
Colocalizes with keratin filaments.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-FAM83H antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
127,122 Da
NCBI Official Full Name
protein FAM83H
NCBI Official Synonym Full Names
family with sequence similarity 83, member H
NCBI Official Symbol
FAM83H
NCBI Official Synonym Symbols
AI3
NCBI Protein Information
protein FAM83H; FAM83H variant 1
UniProt Protein Name
Protein FAM83H
Protein Family
UniProt Gene Name
FAM83H
UniProt Entry Name
FA83H_HUMAN
NCBI Description
The protein encoded by this gene plays an important role in the structural development and calcification of tooth enamel. Defects in this gene are a cause of amelogenesis imperfecta type 3 (AI3). [provided by RefSeq, Mar 2010]
Uniprot Description
FAM83H: May play a major role in the structural organization and calcification of developing enamel. Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3). AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption. Belongs to the FAM83 family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 8q24.3
Biological Process: biomineral formation
Disease: Amelogenesis Imperfecta, Type Iii
Research Articles on FAM83H
Similar Products
Product Notes
The FAM83H fam83h (Catalog #AAA9630420) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAM83H Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FAM83H can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the FAM83H fam83h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAM83H, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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