Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM38A) Polyclonal Antibody, Unconjugated (bs-14991R) at 1:400 overnight at 4°C)
Rabbit FAM38A Polyclonal Antibody | anti-FAM38A antibody
FAM38A Polyclonal Antibody
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM38A) Polyclonal Antibody, Unconjugated (bs-14991R) at 1:400 overnight at 4°C)
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM38A) Polyclonal Antibody, Unconjugated (bs-14991R) at 1:400 overnight at 4°C)
NCBI and Uniprot Product Information
Observed: 235 kDa
NCBI Description
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Uniprot Description
FAM38B: Component of mechanosensitive channel required for rapidly adaptating mechanically activated (MA) currents in DRG neurons. Belongs to the PIEZO family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 18p11.22-p11.21
Cellular Component: plasma membrane
Molecular Function: cation channel activity; mechanically-gated ion channel activity
Biological Process: cation transport; detection of mechanical stimulus; detection of mechanical stimulus involved in sensory perception; regulation of membrane potential; response to mechanical stimulus
Research Articles on FAM38A
Similar Products
Product Notes
The FAM38A piezo2 (Catalog #AAA3015317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAM38A Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Cow, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's FAM38A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-500. Researchers should empirically determine the suitability of the FAM38A piezo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAM38A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
