Rabbit anti-Human FAM189B Polyclonal Antibody | anti-FAM189B antibody

FAM189B Antibody (Center)

Cat. Num. AAA9216384

• Gene Names: FAM189B; COTE1; C1orf2
• Reactivity: Human
• Applications: Western Blot
• Synonyms: FAM189B; Polyclonal Antibody; FAM189B Antibody (Center); Purified Rabbit Polyclonal Antibody (Pab); Protein FAM189B; Protein COTE1; C1orf2; COTE1; anti-FAM189B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Ig
• Specificity: This FAM189B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 365-400 amino acids from the Central region of human FAM189B.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Length: 650

• Applicable Applications for anti-FAM189B antibody: Western Blot (WB)
• Application Notes: WB ~~ 1:2000
• Antigen Source: Human
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-FAM189B Antibody (Center) at 1:2000 dilutionLane 1: human heart lysateLane 2: Jurkat whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 71 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Product Categories/Family for anti-FAM189B antibody

Cell Biology

References

Winfield S.L.,et al.Genome Res. 7:1020-1026(1997). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Ludes-Meyers J.H.,et al.Oncogene 23:5049-5055(2004). Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 390190199
• NCBI GeneID: 10712
• NCBI Accession #: NP_001254537.1
• NCBI GenBank Nucleotide #: NM_001267608.1
• UniProt Accession #: P81408; Q8IXL3; Q9BR66; B1AVS5
• Molecular Weight: 71355
• NCBI Official Full Name: protein FAM189B isoform c
• NCBI Official Synonym Full Names: family with sequence similarity 189 member B
• NCBI Official Symbol: FAM189B
• NCBI Official Synonym Symbols: COTE1; C1orf2
• NCBI Protein Information: protein FAM189B
• UniProt Protein Name: Protein FAM189B
• Protein Family: Protein
• UniProt Gene Name: FAM189B
• UniProt Synonym Gene Names: C1orf2; COTE1
• UniProt Entry Name: F189B_HUMAN

NCBI Description

This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Uniprot Description

FAM189B: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: integral to membrane

Molecular Function: protein binding; WW domain binding