Goat FAIM1 Polyclonal Antibody | anti-FAIM1 antibody

GOAT ANTI HUMAN FAIM1

Cat. Num. AAA223933

• Gene Names: FAIM; FAIM1
• Reactivity: Dog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence)
• Applications: ELISA, Immunohistochemistry, Western Blot
• Synonyms: FAIM1; Polyclonal Antibody; GOAT ANTI HUMAN FAIM1; anti-FAIM1 antibody

• Host: Goat
• Reactivity: Dog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence)
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This item specifically recognises human FAIM1, otherwise known as Fas apoptotic inhibitory molecule 1, a highly conserved inducible effector protein, which acts as a negative regulator of Fas-mediated apoptosis in B cells.
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 0.5mg/ml (varies by lot)
• Sequence Length: 213

• Applicable Applications for anti-FAIM1 antibody: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
• Application Notes: Western Blot: This item detects a band of approximately 25kDa in human lymph node cell lysates.; ELISA: Minimum Dilution: 1/32000; Immunohistology - Paraffin: Minimum Dilution: 2.0; Maximum Dilution: 3.0ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.; Western Blotting: Minimum Dilution: 0.5; Maximum Dilution: 1.0ug/ml
• Perservative Stabilisers: 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin
• Immunogen: Synthetic peptide sequence C-KKYMEDRSKTTN from the internal region of FAIM1 (NP_001028202.1; NP_001028203.1; NP_001028204.1; NP_060617.1).; Histology Positive Control Tissue
• Antiserum Preparation: Antiserum to human FAIM1 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Related Product Information for anti-FAIM1 antibody

MBS223933 specifically recognises human FAIM1, otherwise known as Fas apoptotic inhibitory molecule 1, a highly conserved inducible effector protein, which acts as a negative regulator of Fas-mediated apoptosis in B cells.

NCBI and Uniprot Product Information

• NCBI GI #: 74271911
• NCBI GeneID: 55179
• NCBI Accession #: NP_001028202.1
• NCBI GenBank Nucleotide #: NM_001033030.1
• UniProt Accession #: Q9NVQ4; Q6IAN2
• Molecular Weight: 22,626 Da
• NCBI Official Full Name: fas apoptotic inhibitory molecule 1 isoform a
• NCBI Official Synonym Full Names: Fas apoptotic inhibitory molecule
• NCBI Official Symbol: FAIM
• NCBI Official Synonym Symbols: FAIM1
• NCBI Protein Information: fas apoptotic inhibitory molecule 1
• UniProt Protein Name: Fas apoptotic inhibitory molecule 1
• UniProt Gene Name: FAIM
• UniProt Synonym Gene Names: FAIM1
• UniProt Entry Name: FAIM1_HUMAN

NCBI Description

The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Uniprot Description

FAIM: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Belongs to the FAIM1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: cytoplasm

Biological Process: apoptosis; negative regulation of apoptosis