Rabbit FADD Polyclonal Antibody | anti-FADD antibody
FADD
Gene Names
FADD; GIG3; MORT1
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
FADD; Polyclonal Antibody; Purified Rabbit Anti Human FADD Polyclonal antibody; GIG3; MORT1; anti-FADD antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1725
Applicable Applications for anti-FADD antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 35-181aa of human FADD.
Related Product Information for anti-FADD antibody
Homo sapiens Fas (TNFRSF6)-associated via death domain, mRNA
References
Boldin M P, Varfolomeev E E, Pancer Z. et al. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. Journal of Biological Chemistry. 270 (14):7795-7798 (1995)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
23kDa
NCBI Official Full Name
Homo sapiens Fas (TNFRSF6)-associated via death domain, mRNA
NCBI Official Synonym Full Names
Fas associated via death domain
NCBI Official Symbol
FADD
NCBI Official Synonym Symbols
GIG3; MORT1
NCBI Protein Information
FAS-associated death domain protein
Protein Family
NCBI Description
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
Research Articles on FADD
Similar Products
Product Notes
The FADD (Catalog #AAA8563990) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FADD reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FADD can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-80000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the FADD for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FADD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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