Rabbit anti-Human FABP7 Polyclonal Antibody | anti-FABP7 antibody

FABP7 Antibody

Cat. Num. AAA151313

• Gene Names: FABP7; MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: FABP7 Antibody is affinity chromatography purified via peptide column.
• Synonyms: FABP7; Polyclonal Antibody; FABP7 Antibody; MRG; BLBP; FABPB; B-FABP; Fatty acid-binding protein; brain; Brain lipid-binding protein; fatty acid binding protein 7; anti-FABP7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: FABP7 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 166

• Applicable Applications for anti-FABP7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: FABP7 antibody can be used for detection of FABP7 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.
• Conjugate: Unconjugated
• Immunogen: FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.
• Buffer: FABP7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: FABP7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of FABP7 in human breast tissue lysate with FABP7 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of FABP7 in human breast tissue with FABP7 antibody at 5 μg/mL.)

Related Product Information for anti-FABP7 antibody

FABP7 Antibody: FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could may potentially reduce in vitro cell proliferation and Matrigel invasion.

NCBI and Uniprot Product Information

• NCBI GI #: 119568551
• NCBI GeneID: 2173
• UniProt Accession #: O15540; O14951; Q6IAU7; Q9H047; B2R4L1
• Molecular Weight: 18,829 Da
• NCBI Official Full Name: fatty acid binding protein 7, brain, isoform CRA_b, partial
• NCBI Official Synonym Full Names: fatty acid binding protein 7, brain
• NCBI Official Symbol: FABP7
• NCBI Official Synonym Symbols: MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
• NCBI Protein Information: fatty acid-binding protein, brain; brain lipid binding protein; brain lipid-binding protein; fatty acid-binding protein 7; Hypothetical protein DKFZp547J2313; brain-type fatty acid-binding protein; mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related
• UniProt Protein Name: Fatty acid-binding protein, brain
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP7
• UniProt Synonym Gene Names: BLBP; FABPB; MRG; BLBP; B-FABP
• UniProt Entry Name: FABP7_HUMAN

NCBI Description

The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding; Cell development/differentiation; Cell cycle regulation

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: cell projection; cell soma; cytoplasm; nucleus

Molecular Function: transporter activity; lipid binding

Biological Process: nervous system development; negative regulation of cell proliferation; epithelial cell proliferation; prepulse inhibition; neurogenesis; transport; cell proliferation in forebrain