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Western Blot (WB) (All lanes : Anti-FAAP24 Antibody (N-Term) at 1:1000-1:2000 dilutionLane 1: A549 whole cell lysateLane 2: Jurkat whole cell lysateLane 3: U-2OS whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 24 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human FAAP24 Polyclonal Antibody | anti-FAAP24 antibody

FAAP24 Antibody (N-Term)

Gene Names
FAAP24; C19orf40
Reactivity
Human
Applications
Western Blot
Synonyms
FAAP24; Polyclonal Antibody; FAAP24 Antibody (N-Term); Purified Rabbit Polyclonal Antibody (Pab); Fanconi anemia-associated protein of 24 kDa; C19orf40; anti-FAAP24 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Specificity
This FAAP24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from human FAAP24.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
120
Applicable Applications for anti-FAAP24 antibody
Western Blot (WB)
Application Notes
WB ~~ 1:1000-1:2000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-FAAP24 Antibody (N-Term) at 1:1000-1:2000 dilutionLane 1: A549 whole cell lysateLane 2: Jurkat whole cell lysateLane 3: U-2OS whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 24 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-FAAP24 Antibody (N-Term) at 1:1000-1:2000 dilutionLane 1: A549 whole cell lysateLane 2: Jurkat whole cell lysateLane 3: U-2OS whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 24 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-FAAP24 antibody
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004). Ciccia A.,et al.Mol. Cell 25:331-343(2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23897
NCBI Official Full Name
Fanconi anemia core complex-associated protein 24 isoform 2
NCBI Official Synonym Full Names
Fanconi anemia core complex associated protein 24
NCBI Official Symbol
FAAP24
NCBI Official Synonym Symbols
C19orf40
NCBI Protein Information
Fanconi anemia core complex-associated protein 24
UniProt Protein Name
Fanconi anemia core complex-associated protein 24
UniProt Gene Name
FAAP24
UniProt Entry Name
FAP24_HUMAN

NCBI Description

FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]

Uniprot Description

FAAP24: Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: nucleoplasm; intracellular membrane-bound organelle

Molecular Function: protein binding; DNA binding; chromatin binding

Biological Process: DNA repair

Research Articles on FAAP24

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Product Notes

The FAAP24 faap24 (Catalog #AAA9215920) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAAP24 Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FAAP24 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:1000-1:2000. Researchers should empirically determine the suitability of the FAAP24 faap24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAAP24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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