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Exostosin-like 3 Recombinant Protein | EXTL3 recombinant protein
Recombinant Human Exostosin-like 3
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NCBI and Uniprot Product Information
NCBI Description
This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]
Uniprot Description
EXTL3: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family.
Protein type: Membrane protein, integral; Glycan Metabolism - heparan sulfate biosynthesis; EC 2.4.1.223; Transferase
Chromosomal Location of Human Ortholog: 8p21
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane
Molecular Function: glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; metal ion binding; receptor activity
Biological Process: cellular protein metabolic process; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process; positive regulation of cell growth; unfolded protein response
Research Articles on EXTL3
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Product Notes
The EXTL3 extl3 (Catalog #AAA717253) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-245. The amino acid sequence is listed below: TGYTMLRNGG AGNGGQTCML RWSNRIRLTW LSFTLFVILV FFPLIAHYYL TTLDEADEAG KRIFGPRVGN ELCEVKHVLD LCRIRESVSE ELLQLEAKRQ ELNSEIAKLN LKIEACKKSI ENAKQDLLQL KNVISQTEHS YKELMAQNQP KLSLPIRLLP EKDDAGLPPP KATRGCRLHN CFDYSRCPLT SGFPVYVYDS DQFVFGSYLD PLVKQAFQAT ARANVYVTEN ADIACLYVIL VGEM. It is sometimes possible for the material contained within the vial of "Exostosin-like 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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