Western Blot (WB)
(EXOSC6 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EXOSC6 antibody detected the EXOSC6 protein (arrow).)
Rabbit anti-Human EXOSC6 Polyclonal Antibody | anti-EXOSC6 antibody
EXOSC6, NT (EXOSC6, MTR3, Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog, p11) (Biotin)
Gene Names
EXOSC6; p11; EAP4; MTR3; Mtr3p; hMtr3p
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
EXOSC6; Polyclonal Antibody; NT (EXOSC6; MTR3; Exosome complex component MTR3; Exosome component 6; mRNA transport regulator 3 homolog; p11) (Biotin); p11; anti-EXOSC6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-EXOSC6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(EXOSC6 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EXOSC6 antibody detected the EXOSC6 protein (arrow).)
Western Blot (WB)
(EXOSC6 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EXOSC6 antibody detected the EXOSC6 protein (arrow).)
Related Product Information for anti-EXOSC6 antibody
This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
Product Categories/Family for anti-EXOSC6 antibody
References
Seth, D., et al. J. Hepatol. 48(4):614-627(2008). Lehner, B., et al. Genome Res. 14(7):1315-1323(2004). Raijmakers, R., et al. J. Mol. Biol. 323(4):653-663(2002). van Hoof, A., et al. Curr. Biol. 12 (8), R285-R287 (2002): Raijmakers, R., et al. J. Mol. Biol. 315(4):809-818(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,235 Da
NCBI Official Full Name
exosome complex component MTR3
NCBI Official Synonym Full Names
exosome component 6
NCBI Official Symbol
EXOSC6
NCBI Official Synonym Symbols
p11; EAP4; MTR3; Mtr3p; hMtr3p
NCBI Protein Information
exosome complex component MTR3; hMtr3; exosome complex exonuclease MTR3; mRNA transport regulator 3 homolog; Mtr3 (mRNA transport regulator 3)-homolog; homolog of yeast mRNA transport regulator 3
UniProt Protein Name
Exosome complex component MTR3
UniProt Gene Name
EXOSC6
UniProt Synonym Gene Names
MTR3; hMtr3
UniProt Entry Name
EXOS6_HUMAN
Similar Products
Product Notes
The EXOSC6 exosc6 (Catalog #AAA6297154) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EXOSC6, NT (EXOSC6, MTR3, Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog, p11) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EXOSC6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EXOSC6 exosc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOSC6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
