Rabbit anti-Mouse Excitatory Amino Acid Transporter 2 (EAAT2) Polyclonal Antibody | anti-EAAT2 antibody

Polyclonal Antibody to Excitatory Amino Acid Transporter 2 (EAAT2)

Cat. Num. AAA2112380

• Gene Names: SLC1A2; HBGT; EAAT2; GLT-1; EIEE41
• Reactivity: Mouse
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
• Purity: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Synonyms: Excitatory Amino Acid Transporter 2 (EAAT2); Polyclonal Antibody; Polyclonal Antibody to Excitatory Amino Acid Transporter 2 (EAAT2); SLC1A2; EAAT2; GLT-1; Solute Carrier Family 1 Member 2; Glutamate/aspartate transporter II; Sodium-dependent glutamate/aspartate transporter 2; anti-EAAT2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Specificity: The antibody is a rabbit polyclonal antibody raised against EAAT2. It has been selected for its ability to recognize EAAT2 in immunohistochemical staining and western blotting.
• Purity/Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Form/Format: Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Concentration: 0.4mg/ml (varies by lot)
• Sequence Length: 574

• Applicable Applications for anti-EAAT2 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
• Application Notes: WB: 0.5-2ug/mL; 1:200-800; IHC: 5-20ug/mL; 1:20-80; ICC: 5-20ug/mL; 1:20-80
• Cross Reactivity: Mouse
• Conjugation: None
• Preparation and Storage: Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.; Avoid repeated freeze/thaw cycles.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot; Sample: Recombinant EAAT2, Mouse.)

Product Categories/Family for anti-EAAT2 antibody

Neuro Science

NCBI and Uniprot Product Information

• NCBI GI #: 40254478
• NCBI GeneID: 6506
• NCBI GenBank Nucleotide #: NP_004162.2
• UniProt Accession #: P43004
• NCBI Official Full Name: excitatory amino acid transporter 2 isoform 1
• NCBI Official Synonym Full Names: solute carrier family 1 member 2
• NCBI Official Symbol: SLC1A2
• NCBI Official Synonym Symbols: HBGT; EAAT2; GLT-1; EIEE41
• NCBI Protein Information: excitatory amino acid transporter 2
• UniProt Protein Name: Excitatory amino acid transporter 2
• UniProt Gene Name: SLC1A2
• UniProt Synonym Gene Names: EAAT2; GLT1
• UniProt Entry Name: EAA2_HUMAN

NCBI Description

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]