Rabbit ERCC1 Polyclonal Antibody | anti-ERCC1 antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ERCC1 Polyclonal Antibody

• Gene Names: ERCC1; T12H1.18; T12H1_18; UV REPAIR DEFICIENT 7; UVR7
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: ERCC1; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ERCC1 Polyclonal Antibody; ERCC1 Antibody; DNA excision repair protein ERCC-1; AtERCC1; AtRAD10; EC 3.1.-.-; Ultraviolet hypersensitive 7; ERCC1 RAD10 UVR7 At3g05210 T12H1.18; anti-ERCC1 antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-ERCC1 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana ERCC1 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 15229933
• NCBI GeneID: 819685
• NCBI Accession #: NP_187172.1
• NCBI GenBank Nucleotide #: NM_111394.5
• UniProt Accession #: Q9MA98
• Molecular Weight: 45,748 Da
• NCBI Official Full Name: nucleotide repair protein
• NCBI Official Symbol: ERCC1
• NCBI Official Synonym Symbols: T12H1.18; T12H1_18; UV REPAIR DEFICIENT 7; UVR7
• NCBI Protein Information: nucleotide repair protein
• UniProt Protein Name: DNA excision repair protein ERCC-1
• Protein Family: DNA excision repair protein
• UniProt Gene Name: ERCC1
• UniProt Synonym Gene Names: RAD10; UVR7; AtERCC1; AtRAD10

NCBI Description

encodes a homolog of human ERCC1 protein (yeast RAD10), which is a DNA repair endonuclease. Mutants are sensitive to UV-B and gamma radiation (G2 cell cycle phase arrest) and are defective in dark-repair of pyrimidine pyrimidone dimers. This protein incises the 5' end of damaged DNA, similar to ERCC1/RAD10.

Uniprot Description

Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. In vitro, is involved in chromosomal recombination between tandem repeats in both direct and inverted orientations. May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 phase.