Western Blot (WB)
(EPS8L1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EPS8L1 antibody detected the EPS8L1 protein (arrow).)
Rabbit anti-Human EPS8L1 Polyclonal Antibody | anti-EPS8L1 antibody
EPS8L1, NT (EPS8L1, DRC3, EPS8R1, Epidermal growth factor receptor kinase substrate 8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1) (Biotin)
Gene Names
EPS8L1; DRC3; EPS8R1; PP10566
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
EPS8L1; Polyclonal Antibody; NT (EPS8L1; DRC3; EPS8R1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1) (Biotin); Epidermal growth factor receptor pathway substrate 8-related protein 1; anti-EPS8L1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-EPS8L1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
EPS8L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EPS8L1.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(EPS8L1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EPS8L1 antibody detected the EPS8L1 protein (arrow).)
Western Blot (WB)
(EPS8L1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EPS8L1 antibody detected the EPS8L1 protein (arrow).)
Related Product Information for anti-EPS8L1 antibody
EPS8L1 is a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-EPS8L1 antibody
References
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004). Offenhauser, N., et al. Mol. Biol. Cell 15(1):91-98(2004). Tocchetti, A., et al. Genomics 81(2):234-244(2003). Wu, K., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 16(5):325-327(1999).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,807 Da
NCBI Official Full Name
epidermal growth factor receptor kinase substrate 8-like protein 1 isoform a
NCBI Official Synonym Full Names
EPS8 like 1
NCBI Official Symbol
EPS8L1
NCBI Official Synonym Symbols
DRC3; EPS8R1; PP10566
NCBI Protein Information
epidermal growth factor receptor kinase substrate 8-like protein 1
UniProt Protein Name
Epidermal growth factor receptor kinase substrate 8-like protein 1
UniProt Gene Name
EPS8L1
UniProt Synonym Gene Names
DRC3; EPS8R1; EPS8-like protein 1
UniProt Entry Name
ES8L1_HUMAN
NCBI Description
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
EPS8L1: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 19q13.42
Cellular Component: protein complex; cytoplasm
Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; actin binding
Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction
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Product Notes
The EPS8L1 eps8l1 (Catalog #AAA6296109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPS8L1, NT (EPS8L1, DRC3, EPS8R1, Epidermal growth factor receptor kinase substrate 8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EPS8L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EPS8L1 eps8l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPS8L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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