Immunohistochemistry (IHC)
(Immunochemical staining of human VSIG1 in human stomach with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human VSIG1 Polyclonal Antibody | anti-VSIG1 antibody
Anti-VSIG1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
VSIG1; Polyclonal Antibody; Anti-VSIG1 Antibody; Rabbit Polyclonal; VSIG1 Antibody; Rabbit PAb; Antigen Affinity Purified; V-set and immunoglobulin domain containing 1; Anti-1700062D20Rik Antibody; Anti-dJ889N15.1 Antibody; Anti-GPA34 Antibody; Anti-RP5-889N15.1 Antibody; anti-VSIG1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human VSIG1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-VSIG1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:3000
Immunogen
E Coli-derived Human VSIG1 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human VSIG1 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human VSIG1 in human stomach with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human VSIG1 in human stomach with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human VSIG1 in human gallbladder with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human VSIG1 in human gallbladder with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-VSIG1 antibody
V-set and immunoglobulin domain containing 1 (VSIG1) is a newly discovered member of the immunoglobulin superfamily of proteins, expressed in normal stomach and testis; it is encoded by a gene located on human chromosome X and preferentially expressed in a variety of cancers in humans. VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in the stomach, testis, and certain gastric, esophageal, and ovarian cancers. VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach. VSIG1 possesses tumor-suppressive functions that are translated into the favorable prognosis of VSIG1-expressing gastric cancer (GC) patients. Mouse VSIG1 interacts with Sertoli cells by heterophilic adhesion via its first Ig-like domain.
References
Oidovsambuu O, et al. (2011) Adhesion protein vsig1 is required for the proper differentiation of glandular gastric epithelia. PLoS One 6 (10): e25908.Kim E, et al. (2010) Extracellular domain of v-set and immunoglobulin domain containing 1 (vsig1) interacts with sertoli cell membrane protein, while its pdz-binding motif forms a complex with zo-1. Mol Cells 30 (5): 443-448.Inoue Y, et al. (2017) Characterization of v-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells. Cancer Sci 108 (8): 1701-1714.
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Product Notes
The VSIG1 (Catalog #AAA8109442) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-VSIG1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VSIG1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:3000. Researchers should empirically determine the suitability of the VSIG1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VSIG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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