Goat ENOX2 Polyclonal Antibody | anti-ENOX2 antibody
Goat anti-ENOX2 (APK1, Ecto-NOX Disulfide-thiol Exchanger 2, RP5-875H3.1, COVA1, tNOX, Acytosolic Ovarian Carcinoma Antigen 1)
Western Blot: 0.03ug/ml. A band is detected at ~60kD and 37kD in Human Heart lysates.
NP_872114.1
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Uniprot Description
ENOX2: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. Belongs to the ENOX family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Cell surface; Oxidoreductase; Cytoskeletal
Chromosomal Location of Human Ortholog: Xq25
Cellular Component: extracellular space; cytosol; external side of plasma membrane
Molecular Function: nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity
Biological Process: regulation of growth; cell growth; ultradian rhythm
Research Articles on ENOX2
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Product Notes
The ENOX2 enox2 (Catalog #AAA620010) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ENOX2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA) and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:64,000. Western Blot: 0.03ug/ml. A band is detected at ~60kD and 37kD in Human Heart lysates. Researchers should empirically determine the suitability of the ENOX2 enox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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