Rabbit anti-Human Encephalopsin Polyclonal Antibody | anti-OPN3 antibody

Encephalopsin (OPN3, encephalopsin, opn3, panopsin)

Cat. Num. AAA6009737

• Gene Names: OPN3; ECPN
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Encephalopsin; Polyclonal Antibody; Encephalopsin (OPN3; encephalopsin; opn3; panopsin); Anti -Encephalopsin (OPN3; anti-OPN3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human Encephalopsin. Species sequence homology: Mouse (93/100%).
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.1% sodium azide.

• Applicable Applications for anti-OPN3 antibody: Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Immunohistochemistry.; Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to 2nd extracellular domain of human OPN3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Placenta (formalin-fixed, paraffin-embedded) stained with OPN3 antibody at 5ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC)

(Human Testis (formalin-fixed, paraffin-embedded) stained with OPN3 antibody at 5ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Related Product Information for anti-OPN3 antibody

Encephalopsin expression has been documented in various brain tissues, including the preoptic area and paraventricular nucleus of the hypothalamus, cerebral cortex, cerebellar Purkinje neurons, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord. ESTs have been isolated from human blood, breast, cervix, colon, germ cell, head/neck, kidney, lung, pancreas, placenta, prostate, skin, testis, and uterus cancer libraries, as well as from normal human blood, brain, eye, heart, kidney, liver, liver/spleen, ovary, placenta, prostate, skin, testis, and B-cell/lung/testis libraries.

Product Categories/Family for anti-OPN3 antibody

Antibodies; Abs to G Protein Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 4894952
• NCBI GeneID: 23596
• UniProt Accession #: Q9H1Y3; Q8IX08; Q9Y344
• Molecular Weight: 44,873 Da
• NCBI Official Full Name: encephalopsin
• NCBI Official Synonym Full Names: opsin 3
• NCBI Official Symbol: OPN3
• NCBI Official Synonym Symbols: ECPN
• NCBI Protein Information: opsin-3; encephalopsin; opsin 3 (encephalopsin, panopsin)
• UniProt Protein Name: Opsin-3
• Protein Family: Opsin
• UniProt Gene Name: OPN3
• UniProt Synonym Gene Names: ECPN
• UniProt Entry Name: OPN3_HUMAN

NCBI Description

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]

Uniprot Description

encephalopsin: May play a role in encephalic photoreception. Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: integral to plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; photoreceptor activity; G-protein coupled photoreceptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of light stimulus; phototransduction; regulation of circadian rhythm; protein-chromophore linkage; detection of visible light