Western Blot (WB)
(EMP2 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the EMP2 antibody detected the EMP2 protein (arrow).)
Rabbit anti-Mouse EMP2 Polyclonal Antibody | anti-EMP2 antibody
EMP2, CT (EMP2, XMP, Epithelial membrane protein 2, Protein XMP) (APC)
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(EMP2 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the EMP2 antibody detected the EMP2 protein (arrow).)
Western Blot (WB)
(EMP2 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the EMP2 antibody detected the EMP2 protein (arrow).)
Immunohistochemistry (IHC)
(EMP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EMP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(EMP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EMP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). [provided by RefSeq, Mar 2015]
Uniprot Description
EMP2: Belongs to the PMP-22/EMP/MP20 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16p13.2
Cellular Component: Golgi membrane; Golgi apparatus; cell surface; apical part of cell; apical plasma membrane; cytoplasm; integral to membrane; plasma membrane; caveola; cytoplasmic vesicle; nucleus; lipid raft
Molecular Function: integrin binding; protein binding; kinase binding; protein kinase binding
Biological Process: cell death; regulation of kinase activity; cell migration; blood vessel endothelial cell migration; cell-matrix adhesion; actin filament organization; bleb formation; lipid raft formation; regulation of angiogenesis; cell proliferation; regulation of glomerular filtration; early endosome to late endosome transport; positive regulation of cell proliferation; activation of protein kinase activity; positive regulation of cell-matrix adhesion; cell adhesion; embryo implantation; T cell mediated cytotoxicity
Disease: Nephrotic Syndrome, Type 10
Research Articles on EMP2
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Product Notes
The EMP2 emp2 (Catalog #AAA6295491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EMP2, CT (EMP2, XMP, Epithelial membrane protein 2, Protein XMP) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EMP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EMP2 emp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EMP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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