Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using EMP1 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human EMP1 Polyclonal Antibody | anti-EMP1 antibody
EMP1 Antibody
Gene Names
EMP1; TMP; CL-20; EMP-1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
EMP1; Polyclonal Antibody; EMP1 Antibody; TMP; CL-20; EMP-1; anti-EMP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total EMP1 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.2mg/ml (varies by lot)
Sequence Length
157
Applicable Applications for anti-EMP1 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1: 20-100
Immunogen
Synthetic peptide of human EMP1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using EMP1 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using EMP1 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using EMP1 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using EMP1 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-EMP1 antibody
Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.
Product Categories/Family for anti-EMP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,252 Da
NCBI Official Full Name
epithelial membrane protein 1
NCBI Official Synonym Full Names
epithelial membrane protein 1
NCBI Official Symbol
EMP1
NCBI Official Synonym Symbols
TMP; CL-20; EMP-1
NCBI Protein Information
epithelial membrane protein 1
UniProt Protein Name
Epithelial membrane protein 1
Protein Family
UniProt Gene Name
EMP1
UniProt Synonym Gene Names
B4B; TMP; EMP-1
UniProt Entry Name
EMP1_HUMAN
Uniprot Description
EMP1: Belongs to the PMP-22/EMP/MP20 family.
Protein type: Cell development/differentiation; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: membrane; plasma membrane
Molecular Function: protein binding
Biological Process: bleb formation; cell death; cell proliferation; epidermis development; multicellular organismal development
Research Articles on EMP1
Similar Products
Product Notes
The EMP1 emp1 (Catalog #AAA9417139) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EMP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EMP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the EMP1 emp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EMP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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