Western Blot (WB)
(Host: RabbitTarget Name: EML4Sample Type: PANC1 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Rabbit anti-Human EML4 Polyclonal Antibody | anti-EML4 antibody
EML4 Antibody - C-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: EML4Sample Type: PANC1 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: EML4Sample Type: PANC1 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Target Description: EML4 may modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic
By similarity.
Subcellular location: Cytoplasm › cytoskeleton
Potential.
Developmental stage: Strongly overexpressed during mitosis.
Sequence similarities: Belongs to the WD repeat EMAP family.Contains 9 WD repeats.
Sequence caution: The sequence AAI04648.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.The sequence BAA91919.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on EML4
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Product Notes
The EML4 eml4 (Catalog #AAA3215282) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EML4 Antibody - C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EML4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the EML4 eml4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ENSLEQTVEP SEDHSEEESE EGSGDLGEPL YEEPCNEISK EQAKATLLED. It is sometimes possible for the material contained within the vial of "EML4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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