Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term). MBS9214452 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Rabbit ELAVL3 Polyclonal Antibody | anti-ELAVL3 antibody
ELAVL3 Antibody (N-term)
IHC-P~~1:10~50
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term). MBS9214452 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term). MBS9214452 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term). MBS9214452 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term). MBS9214452 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Immunohistochemistry (IHC)
(ELAVL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELAVL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ELAVL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELAVL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
neural-specific RNA-binding protein which contains three RNP-type
RNA recognition motifs. The observation that ELAVL3 is one of
several Hu antigens (neuronal-specific RNA-binding proteins)
recognized by the anti-Hu serum antibody present in sera from
patients with paraneoplastic encephalomyelitis and sensory
neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two
alternatively spliced transcript variants encoding distinct
isoforms have been found for this gene.
Park, S., et al. Mol. Cell. Biol. 20(13):4765-4772(2000)
King, P.H. Nucleic Acids Res. 28 (7), E20 (2000) :
Sakai, K., et al. Biochem. Biophys. Res. Commun. 256(2):263-268(1999)
Van Tine, B.A., et al. Genomics 53(3):296-299(1998)
NCBI and Uniprot Product Information
NCBI Description
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ELAVL3: Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 19p13.2
Molecular Function: nucleotide binding; AU-rich element binding
Biological Process: nervous system development; cell differentiation
Research Articles on ELAVL3
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Product Notes
The ELAVL3 elavl3 (Catalog #AAA9214452) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 71-99. The ELAVL3 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's ELAVL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000 IHC-P~~1:10~50. Researchers should empirically determine the suitability of the ELAVL3 elavl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELAVL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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