Rabbit anti-Human EID3 Polyclonal Antibody | anti-EID3 antibody
EID3 Antibody
Gene Names
EID3; NS4EB; NSE4B; NSMCE4B
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
EID3; Polyclonal Antibody; EID3 Antibody; E1A-like inhibitor of differentiation 3; EID 3; EID-1-like inhibitor of differentiation 3; EID-3; EID3_HUMAN; EP300 interacting inhibitor of differentiation 3; EP300-interacting inhibitor of differentiation 3; FLJ25832; Non-SMC element 4; S. cerevisiae; homolog of; B; Non-structural maintenance of chromosomes element 4 homolog B; NSE4B; NSMCE4B; anti-EID3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
EID3 Antibody detects endogenous levels of EID3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-EID3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human EID3.
Conjugation
Unconjugated
Similarity
Belongs to the NSE4 family.
Subunit Structure
Component of the SMC5-SMC6 complex which consists at least of SMC5, SMC6, NSMCE2, NSMCE1, NSMCE4A or EID3 and NSMCE3; EID3 seems to be a testis-specific subunit. NSMCE1, NSMCE4A or EID3 and NSMCE3 probably form a subcomplex that bridges the head domains of the SMC5:SMC6 heterodimer. Homodimer, and heterodimer with EID2 (By similarity). Interacts with the C-terminal region of CREBBP.
Tissue Specificity
Highly expressed in testis.
Function
Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.
Note
May shuttle between nucleus and cytoplasm.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-EID3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,168 Da
NCBI Official Full Name
EP300-interacting inhibitor of differentiation 3
NCBI Official Synonym Full Names
EP300 interacting inhibitor of differentiation 3
NCBI Official Symbol
EID3
NCBI Official Synonym Symbols
NS4EB; NSE4B; NSMCE4B
NCBI Protein Information
EP300-interacting inhibitor of differentiation 3; E1A-like inhibitor of differentiation 3; EID-1-like inhibitor of differentiation 3; EID-3; EID3; non-SMC element 4 homolog B; non-structural maintenance of chromosomes element 4 homolog B
UniProt Protein Name
EP300-interacting inhibitor of differentiation 3
Protein Family
UniProt Gene Name
EID3
UniProt Synonym Gene Names
EID-3; NS4EB; Non-SMC element 4 homolog B
UniProt Entry Name
EID3_HUMAN
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Product Notes
The EID3 eid3 (Catalog #AAA9630491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EID3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EID3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the EID3 eid3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EID3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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