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Western Blot (WB) (Host: RabbitTarget Name: ECHPSample Type: Fetal Liver lysatesAntibody Dilution: 1.0ug/ml)

Rabbit anti-Human EHHADH Polyclonal Antibody | anti-EHHADH antibody

EHHADH Antibody - middle region

Gene Names
EHHADH; LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
EHHADH; Polyclonal Antibody; EHHADH Antibody - middle region; anti-EHHADH antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: VIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKEL
Sequence Length
723
Applicable Applications for anti-EHHADH antibody
Western Blot (WB)
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human ECHP
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Host: RabbitTarget Name: ECHPSample Type: Fetal Liver lysatesAntibody Dilution: 1.0ug/ml)

Western Blot (WB) (Host: RabbitTarget Name: ECHPSample Type: Fetal Liver lysatesAntibody Dilution: 1.0ug/ml)
Related Product Information for anti-EHHADH antibody
This is a rabbit polyclonal antibody against ECHP. It was validated on Western Blot

Target Description: The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-EHHADH antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
79kDa
NCBI Official Full Name
peroxisomal bifunctional enzyme isoform 1
NCBI Official Synonym Full Names
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
NCBI Official Symbol
EHHADH
NCBI Official Synonym Symbols
LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE
NCBI Protein Information
peroxisomal bifunctional enzyme
UniProt Protein Name
Peroxisomal bifunctional enzyme
UniProt Gene Name
EHHADH
UniProt Synonym Gene Names
ECHD; PBE; PBFE
UniProt Entry Name
ECHP_HUMAN

NCBI Description

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

EHHADH: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Amino Acid Metabolism - tryptophan; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 4.2.1.17; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - butanoate; Oxidoreductase; Isomerase; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid; Lyase; Amino Acid Metabolism - lysine degradation; EC 5.3.3.8; EC 1.1.1.35

Chromosomal Location of Human Ortholog: 3q26.3-q28

Cellular Component: mitochondrion; peroxisome; cytosol

Molecular Function: enzyme binding; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; coenzyme binding; 3-hydroxyacyl-CoA dehydrogenase activity; receptor binding

Biological Process: fatty acid beta-oxidation; internal protein amino acid acetylation

Disease: Fanconi Renotubular Syndrome 3

Research Articles on EHHADH

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Product Notes

The EHHADH ehhadh (Catalog #AAA3220244) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EHHADH Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EHHADH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the EHHADH ehhadh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VIAVDSDKNQ LATANKMITS VLEKEASKMQ QSGHPWSGPK PRLTSSVKEL. It is sometimes possible for the material contained within the vial of "EHHADH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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