Rabbit anti-Human EGR3 Polyclonal Antibody | anti-EGR3 antibody

EGR3 Antibody

Cat. Num. AAA9404851

• Gene Names: EGR3; EGR-3; PILOT
• Reactivity: Human
• Applications: Western Blot
• Purity: Antigen affinity purification.
• Synonyms: EGR3; Polyclonal Antibody; EGR3 Antibody; EGR-3; PILOT; anti-EGR3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total EGR3 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.4 mg/ml (varies by lot)
• Sequence Length: 349

• Applicable Applications for anti-EGR3 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:200-1:1000
• Immunogen Type: Protein
• Immunogen Description: Fusion protein corresponding to residues near the C terminal of human early growth response 3
• Target Name: EGR3
• Preparation and Storage: Store at -20 degree C

Testing Data

(Gel: 8%SDS-PAGE Lysate: 40ug Jurkat cellPrimary antibody: 1/300 dilution Secondary antibody dilution: 1/8000Exposure time: 3 minutes)

Related Product Information for anti-EGR3 antibody

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development.

Product Categories/Family for anti-EGR3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 315467854
• NCBI GeneID: 1960
• NCBI Accession #: NP_001186809.1
• NCBI GenBank Nucleotide #: NM_001199880.1
• UniProt Accession #: Q06889; Q2M3W2; A8K8U9; B4DHJ5; E7EW38
• Molecular Weight: 38,478 Da
• NCBI Official Full Name: early growth response protein 3 isoform 2
• NCBI Official Synonym Full Names: early growth response 3
• NCBI Official Symbol: EGR3
• NCBI Official Synonym Symbols: EGR-3; PILOT
• NCBI Protein Information: early growth response protein 3
• UniProt Protein Name: Early growth response protein 3
• Protein Family: Early growth response protein
• UniProt Gene Name: EGR3
• UniProt Synonym Gene Names: PILOT; EGR-3
• UniProt Entry Name: EGR3_HUMAN

NCBI Description

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]

Uniprot Description

EGR3: Probable transcription factor involved in muscle spindle development. Belongs to the EGR C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 8p23-p21

Cellular Component: cytoplasm; nucleus

Molecular Function: DNA binding; metal ion binding; transcription factor activity

Biological Process: circadian rhythm; positive regulation of T cell differentiation in the thymus; muscle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cell migration during sprouting angiogenesis; neuromuscular synaptic transmission; positive regulation of endothelial cell proliferation; regulation of gamma-delta T cell differentiation; peripheral nervous system development; negative regulation of apoptosis