Rabbit anti-Human, Mouse EDA Polyclonal Antibody | anti-EDA antibody

EDA Antibody

Cat. Num. AAA9507426

• Gene Names: EDA; ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Synonyms: EDA; Polyclonal Antibody; EDA Antibody; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein; anti-EDA antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: EDA Antibody detects endogenous levels of EDA protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 386

• Applicable Applications for anti-EDA antibody: Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
• Application Notes: WB: 1:500~1:2000; IHC-P: 1:100-1:300; ELISA: 1:10000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDA.
• Immunogen Range: 120-170
• Preparation and Storage: Store at -20 degree C for 1 year.

NCBI and Uniprot Product Information

• NCBI GI #: 54112101
• NCBI GeneID: 1896
• NCBI Accession #: NP_001005609.1
• NCBI GenBank Nucleotide #: NM_001005609.1
• UniProt Accession #: Q92838; O75910; Q5JS00; Q5JUM7; Q9UP77; Q9Y6L0; Q9Y6L1; Q9Y6L2; A0AUZ2; A2A337; B7ZLU2; B7ZLU4
• Molecular Weight: 41
• NCBI Official Full Name: ectodysplasin-A isoform 2
• NCBI Official Synonym Full Names: ectodysplasin A
• NCBI Official Symbol: EDA
• NCBI Official Synonym Symbols: ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1
• NCBI Protein Information: ectodysplasin-A
• UniProt Protein Name: Ectodysplasin-A
• Protein Family: Ectodysplasin
• UniProt Gene Name: EDA
• UniProt Synonym Gene Names: ED1; EDA2; EDA protein

NCBI Description

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R (PubMed:8696334, PubMed:11039935, PubMed:27144394). May also play a role in cell adhesion ().