Western Blot (WB)
(ECSCR Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ECSCR antibody detected the ECSCR protein (arrow).)
Rabbit anti-Human, Mouse ECSCR Polyclonal Antibody | anti-ECSCR antibody
ECSCR, CT (ECSCR, ECSM2, Endothelial cell-specific chemotaxis regulator, Endothelial cell-specific molecule 2) (FITC)
Gene Names
ECSCR; ARIA; ECSM2
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ECSCR; Polyclonal Antibody; CT (ECSCR; ECSM2; Endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2) (FITC); Endothelial cell-specific molecule 2; anti-ECSCR antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-ECSCR antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ECSCR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human ECSCR.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(ECSCR Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ECSCR antibody detected the ECSCR protein (arrow).)
Western Blot (WB)
(ECSCR Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ECSCR antibody detected the ECSCR protein (arrow).)
Related Product Information for anti-ECSCR antibody
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it may be involved in cell shape changes and EGF-induced cell migration. This gene could play a role in angiogenesis-related diseases.
Product Categories/Family for anti-ECSCR antibody
References
Ikeda, K., et al. Proc. Natl. Acad. Sci. U.S.A. 106(20):8227-8232(2009). Ma, F., et al. Genes Cells 14(3):281-293(2009). Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009): Armstrong, L.J., et al. Arterioscler. Thromb. Vasc. Biol. 28(9):1640-1646(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,295 Da
NCBI Official Full Name
endothelial cell-specific chemotaxis regulator isoform 1
NCBI Official Synonym Full Names
endothelial cell surface expressed chemotaxis and apoptosis regulator
NCBI Official Symbol
ECSCR
NCBI Official Synonym Symbols
ARIA; ECSM2
NCBI Protein Information
endothelial cell-specific chemotaxis regulator
UniProt Protein Name
Endothelial cell-specific chemotaxis regulator
Protein Family
UniProt Gene Name
ECSCR
UniProt Synonym Gene Names
ECSM2; ARIA
UniProt Entry Name
ECSCR_HUMAN
NCBI Description
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Uniprot Description
ECSM2: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis via modulation of the actin cytoskeleton. Belongs to the ECSCR family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: cytoplasm; plasma membrane; integral to membrane
Biological Process: apoptosis; angiogenesis; cell differentiation; chemotaxis
Research Articles on ECSCR
Similar Products
Product Notes
The ECSCR ecscr (Catalog #AAA6294272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECSCR, CT (ECSCR, ECSM2, Endothelial cell-specific chemotaxis regulator, Endothelial cell-specific molecule 2) (FITC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ECSCR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ECSCR ecscr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECSCR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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