Western Blot (WB)
(Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Chicken ECRG1 Polyclonal Antibody | anti-TMPRSS11A antibody
ECRG1 Antibody
Gene Names
TMPRSS11A; ECRG1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
ECRG1 Antibody is affinity chromatography purified via peptide column.
Synonyms
ECRG1; Polyclonal Antibody; ECRG1 Antibody; HATL1; HESP; Transmembrane protease serine 11A; Airway trypsin-like protease 1; transmembrane protease; serine 11A; anti-TMPRSS11A antibody
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgY
Specificity
At least two isoforms of ECRG1 are known to exist; ECRG1 antibody is predicted to not cross-react with other ECRG family members.
Purity/Purification
ECRG1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
421
Applicable Applications for anti-TMPRSS11A antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 mug/mL.
Conjugate
Unconjugated
Immunogen
ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1.
Buffer
ECRG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ECRG1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-TMPRSS11A antibody
ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,254 Da
NCBI Official Full Name
transmembrane protease serine 11A isoform 1
NCBI Official Synonym Full Names
transmembrane protease, serine 11A
NCBI Official Symbol
TMPRSS11A
NCBI Official Synonym Symbols
ECRG1
NCBI Protein Information
transmembrane protease serine 11A; airway trypsin-like protease 1; epidermal type II transmembrane serine protease; epidermal type-II transmembrane serine protease; esophageal cancer-susceptibility gene 1 protein
UniProt Protein Name
Transmembrane protease serine 11A
Protein Family
UniProt Gene Name
TMPRSS11A
UniProt Synonym Gene Names
ECRG1; HATL1; HESP
UniProt Entry Name
TM11A_HUMAN
Uniprot Description
TMPRSS11A: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.-; Protease; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q13.2
Cellular Component: integral to plasma membrane; extracellular region
Molecular Function: serine-type endopeptidase activity
Biological Process: cell cycle; proteolysis
Research Articles on TMPRSS11A
Similar Products
Product Notes
The TMPRSS11A tmprss11a (Catalog #AAA150872) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The ECRG1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ECRG1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 mug/mL. Researchers should empirically determine the suitability of the TMPRSS11A tmprss11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECRG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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