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Goat Eat2A/Eat2B Polyclonal Antibody | anti-Sh2d1b antibody

Goat anti-Eat2A/Eat2B (mouse) Antibody

Gene Names
Sh2d1b1; Eat2; EAT-2; Eat2a; EAT-2A; Sh2d1b
Reactivity
Expected from sequence similarity: Mouse
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Eat2A/Eat2B; Polyclonal Antibody; Goat anti-Eat2A/Eat2B (mouse) Antibody; Sh2d1b; SH2 domain protein 1B [Mus musculus]; MGI: 1349420; EAT-2; EAT-2A; Eat2; Eat2a; EWS/FLI1 activated transcript 2; Sh2d1b2; SH2 domain protein 1B2; EAT-2B; Eat2b; Sh2d1c; EAT-2-related transducer; Sh2d1b antibody; SH2 domain protein 1B [Mus musculus] antibody; MGI: 1349420 antibody; EAT-2 antibody; EAT-2A antibody; Eat2 antibody; Eat2a antibody; EWS/FLI1 activated transcript 2 antibody; Sh2d1b2 antibody; SH2 domain protein 1B2 antibody; EAT-2B antibody; Eat2b antibody; Sh2d1c antibody; EAT-2-related transducer antibody; Eat2A / Eat2B (mouse); anti-Sh2d1b antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Mouse
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
ELNVYENTDEEYVD
Sequence Length
132
Applicable Applications for anti-Sh2d1b antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is investigative grade.
Immunogen
Peptide with sequence C-ELNVYENTDEEYVD, from the C Terminus of the protein sequence according to NP_036139.2.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,259 Da
NCBI Official Full Name
SH2 domain protein 1B
NCBI Official Synonym Full Names
SH2 domain containing 1B1
NCBI Official Symbol
Sh2d1b1
NCBI Official Synonym Symbols
Eat2; EAT-2; Eat2a; EAT-2A; Sh2d1b
NCBI Protein Information
SH2 domain-containing protein 1B
UniProt Protein Name
SH2 domain-containing protein 1B
UniProt Gene Name
Sh2d1b
UniProt Synonym Gene Names
Eat2; Eat2a; Sh2d1b1; EAT-2
UniProt Entry Name
SH21B_MOUSE

Uniprot Description

SH2D1B: Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Cellular Component: intracellular

Molecular Function: phosphotyrosine binding; protein binding

Biological Process: adaptive immune response; immune system process; innate immune response; leukocyte activation during immune response; natural killer cell inhibitory signaling pathway; negative regulation of interferon-gamma production; negative regulation of natural killer cell mediated cytotoxicity; negative regulation of peptidyl-tyrosine phosphorylation; peptidyl-tyrosine phosphorylation; positive regulation of innate immune response; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated immunity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of signal transduction

Research Articles on Sh2d1b

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Product Notes

The Sh2d1b sh2d1b (Catalog #AAA421912) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Eat2A/Eat2B (mouse) Antibody reacts with Expected from sequence similarity: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Eat2A/Eat2B can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is investigative grade. Researchers should empirically determine the suitability of the Sh2d1b sh2d1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ELNVYENTDE EYVD. It is sometimes possible for the material contained within the vial of "Eat2A/Eat2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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