Western Blot (WB)
(Gel: 6%SDS-PAGE Lysate: 40 μ g Lane: HT-29 cell Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
Rabbit anti-Human E2F8 Polyclonal Antibody | anti-E2F8 antibody
E2F8 Antibody
Immunohistochemistry: 1:20-1:100
Western Blot (WB)
(Gel: 6%SDS-PAGE Lysate: 40 μ g Lane: HT-29 cell Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
Western Blot (WB)
(Gel: 6%SDS-PAGE Lysate: 40 μ g Lane: HT-29 cell Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
NCBI and Uniprot Product Information
Uniprot Description
E2F8: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 11p15.1
Molecular Function: protein binding; transcription corepressor activity; transcription factor activity
Biological Process: cell cycle comprising mitosis without cytokinesis; negative regulation of cytokinesis; negative regulation of transcription from RNA polymerase II promoter; placenta development; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis
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Product Notes
The E2F8 e2f8 (Catalog #AAA9416376) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The E2F8 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's E2F8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:200-1:1000 Immunohistochemistry: 1:20-1:100. Researchers should empirically determine the suitability of the E2F8 e2f8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "E2F8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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