Rabbit anti-Human E2F5 Polyclonal Antibody | anti-E2F5 antibody

E2F5 Antibody, Biotin conjugated

Cat. Num. AAA7109203

• Gene Names: E2F5; E2F-5
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: E2F5; Polyclonal Antibody; E2F5 Antibody; Biotin conjugated; Transcription factor E2F5; E2F-5; anti-E2F5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 345

• Applicable Applications for anti-E2F5 antibody: ELISA (EIA)
• Immunogen: Recombinant Human Transcription factor E2F5 protein (193-298AA)
• Conjugation: Biotin
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-E2F5 antibody

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

Product Categories/Family for anti-E2F5 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 134142809
• NCBI GeneID: 1875
• NCBI Accession #: NP_001077057.1
• NCBI GenBank Nucleotide #: NM_001083588.1
• UniProt Accession #: Q15329; Q16601; Q92756; E9PBN9
• Molecular Weight: 20,192 Da
• NCBI Official Full Name: transcription factor E2F5 isoform 2
• NCBI Official Synonym Full Names: E2F transcription factor 5
• NCBI Official Symbol: E2F5
• NCBI Official Synonym Symbols: E2F-5
• NCBI Protein Information: transcription factor E2F5
• UniProt Protein Name: Transcription factor E2F5
• Protein Family: Transcription factor
• UniProt Gene Name: E2F5
• UniProt Synonym Gene Names: E2F-5

NCBI Description

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.