Rabbit anti-Human, Mouse DYX1C1 Polyclonal Antibody | anti-DYX1C1 antibody

DYX1C1 (Dyslexia Susceptibility 1 Candidate Gene 1 Protein, EKN1, FLJ37882, MGC70618, RD) (PE)

Cat. Num. AAA6376853

• Gene Names: DNAAF4; RD; DYX1; EKN1; DYXC1; CILD25; DYX1C1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: DYX1C1; Polyclonal Antibody; DYX1C1 (Dyslexia Susceptibility 1 Candidate Gene 1 Protein; EKN1; FLJ37882; MGC70618; RD) (PE); anti-DYX1C1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human DYX1C1. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 1468

• Applicable Applications for anti-DYX1C1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human DYX1C1, aa1-381 (AAH62564.1).
• Immunogen Sequence: MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEGRKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAVCHLKLKNLHKAIEDSSKEFCSLEGIECQASEPKLSHHIPSDLHVYIQMA
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(DYX1C1 rabbit polyclonal antibody. Western Blot analysis of DYX1C1 expression in mouse kidney.)

Western Blot (WB)

(Western Blot analysis of DYX1C1 expression in transfected 293T cell line by DYX1C1 polyclonal antibody. Lane 1: DYX1C1 transfected lysate (44.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-DYX1C1 antibody

Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.

Product Categories/Family for anti-DYX1C1 antibody

Antibodies; Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 38565951
• NCBI GeneID: 161582
• NCBI Official Full Name: Homo sapiens dyslexia susceptibility 1 candidate 1, mRNA
• NCBI Official Synonym Full Names: dynein axonemal assembly factor 4
• NCBI Official Symbol: DNAAF4
• NCBI Official Synonym Symbols: RD; DYX1; EKN1; DYXC1; CILD25; DYX1C1
• NCBI Protein Information: dynein assembly factor 4, axonemal
• Protein Family: Dyslexia susceptibility 1 candidate gene 1 protein

NCBI Description

This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011]