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Western Blot (WB) (Western blot analysis of the lysates from COLO205 cells using DYR1B antibody.)

Rabbit anti-Human, Mouse DYR1B Polyclonal Antibody | anti-DYR1B antibody

DYR1B Antibody

Gene Names
DYRK1B; MIRK; AOMS3
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
DYR1B; Polyclonal Antibody; DYR1B Antibody; Dual-specificity tyrosine-phosphorylation regulated kinase 1B; MIRK; Mirk protein kinase; kinase DYRK1B; anti-DYR1B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
DYR1B Antibody detects endogenous levels of DYR1B.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
601
Applicable Applications for anti-DYR1B antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human DYR1B.
Immunogen Range
307-356
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of the lysates from COLO205 cells using DYR1B antibody.)

Western Blot (WB) (Western blot analysis of the lysates from COLO205 cells using DYR1B antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69 kDa
NCBI Official Full Name
dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p69
NCBI Official Synonym Full Names
dual specificity tyrosine phosphorylation regulated kinase 1B
NCBI Official Symbol
DYRK1B
NCBI Official Synonym Symbols
MIRK; AOMS3
NCBI Protein Information
dual specificity tyrosine-phosphorylation-regulated kinase 1B
UniProt Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
UniProt Gene Name
DYRK1B
UniProt Synonym Gene Names
MIRK

NCBI Description

This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Uniprot Description

Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).

Research Articles on DYR1B

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Product Notes

The DYR1B dyrk1b (Catalog #AAA9509409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYR1B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DYR1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the DYR1B dyrk1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYR1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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