Western Blot (WB)
(DSN1 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DSN1 antibody detected the DSN1 protein (arrow).)
Rabbit anti-Human DSN1 Polyclonal Antibody | anti-DSN1 antibody
DSN1 Antibody (C-term)
Gene Names
DSN1; KNL3; MIS13; hKNL-3; C20orf172; dJ469A13.2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DSN1; Polyclonal Antibody; DSN1 Antibody (C-term); Kinetochore-associated protein DSN1 homolog; C20orf172; MIS13; anti-DSN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human DSN1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
257-286
Sequence Length
249
Applicable Applications for anti-DSN1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(DSN1 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DSN1 antibody detected the DSN1 protein (arrow).)
Western Blot (WB)
(DSN1 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DSN1 antibody detected the DSN1 protein (arrow).)
Related Product Information for anti-DSN1 antibody
This gene encodes a kinetochore protein that functions as
part of the minichromosome instability-12 centromere complex. The
encoded protein is required for proper kinetochore assembly and
progression through the cell cycle. Alternative splicing results in
multiple transcript variants.
part of the minichromosome instability-12 centromere complex. The
encoded protein is required for proper kinetochore assembly and
progression through the cell cycle. Alternative splicing results in
multiple transcript variants.
Product Categories/Family for anti-DSN1 antibody
References
Yang, Y., et al. J. Biol. Chem. 283(39):26726-26736(2008)
Cheeseman, I.M., et al. Nat. Rev. Mol. Cell Biol. 9(1):33-46(2008)
Kiyomitsu, T., et al. Dev. Cell 13(5):663-676(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)
Cheeseman, I.M., et al. Nat. Rev. Mol. Cell Biol. 9(1):33-46(2008)
Kiyomitsu, T., et al. Dev. Cell 13(5):663-676(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40067
NCBI Official Full Name
kinetochore-associated protein DSN1 homolog isoform 1
NCBI Official Synonym Full Names
DSN1, MIS12 kinetochore complex component
NCBI Official Symbol
DSN1
NCBI Official Synonym Symbols
KNL3; MIS13; hKNL-3; C20orf172; dJ469A13.2
NCBI Protein Information
kinetochore-associated protein DSN1 homolog
UniProt Protein Name
Kinetochore-associated protein DSN1 homolog
Protein Family
UniProt Gene Name
DSN1
UniProt Synonym Gene Names
C20orf172; MIS13
UniProt Entry Name
DSN1_HUMAN
NCBI Description
This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Uniprot Description
DSN1: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 20q11.23
Cellular Component: cytoplasm; nucleus; cytosol; MIS12/MIND type complex
Molecular Function: protein binding
Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
Research Articles on DSN1
Similar Products
Product Notes
The DSN1 dsn1 (Catalog #AAA9204465) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 257-286. The DSN1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DSN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the DSN1 dsn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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