SDS-PAGE
Kinetochore-associated protein DSN1 homolog (DSN1) Recombinant Protein | DSN1 recombinant protein
Recombinant Human Kinetochore-associated protein DSN1 homolog (DSN1)
Gene Names
DSN1; KNL3; MIS13; hKNL-3; C20orf172; dJ469A13.2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Kinetochore-associated protein DSN1 homolog (DSN1); Recombinant Human Kinetochore-associated protein DSN1 homolog (DSN1); Kinetochore-associated protein DSN1 homolog; DSN1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-356aa; Full Length
Sequence
MTSVTRSEIIDEKGPVMSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sequence Length
356
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-PAGE
SDS-PAGE
Related Product Information for DSN1 recombinant protein
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
Product Categories/Family for DSN1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
67.1 kDa
NCBI Official Full Name
kinetochore-associated protein DSN1 homolog isoform 1
NCBI Official Synonym Full Names
DSN1, MIS12 kinetochore complex component
NCBI Official Symbol
DSN1
NCBI Official Synonym Symbols
KNL3; MIS13; hKNL-3; C20orf172; dJ469A13.2
NCBI Protein Information
kinetochore-associated protein DSN1 homolog; kinetochore null 3 homolog; DSN1, MIND kinetochore complex component, homolog
UniProt Protein Name
Kinetochore-associated protein DSN1 homolog
Protein Family
UniProt Gene Name
DSN1
UniProt Synonym Gene Names
C20orf172; MIS13
UniProt Entry Name
DSN1_HUMAN
NCBI Description
This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Uniprot Description
DSN1: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 20q11.23
Cellular Component: cytoplasm; nucleus; cytosol; MIS12/MIND type complex
Molecular Function: protein binding
Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
Research Articles on DSN1
Similar Products
Product Notes
The DSN1 dsn1 (Catalog #AAA1444956) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-356aa; Full Length. The amino acid sequence is listed below: MTSVTRSEII DEKGPVMSKT HDHQLESSLS PVEVFAKTSA SLEMNQGVSE ERIHLGSSPK KGGNCDLSHQ ERLQSKSLHL SPQEQSASYQ DRRQSWRRAS MKETNRRKSL HPIHQGITEL SRSISVDLAE SKRLGCLLLS SFQFSIQKLE PFLRDTKGFS LESFRAKASS LSEELKHFAD GLETDGTLQK CFEDSNGKAS DFSLEASVAE MKEYITKFSL ERQTWDQLLL HYQQEAKEIL SRGSTEAKIT EVKVEPMTYL GSSQNEVLNT KPDYQKILQN QSKVFDCMEL VMDELQGSVK QLQAFMDEST QCFQKVSVQL GKRSMQQLDP SPARKLLKLQ LQNPPAIHGS GSGSCQ. It is sometimes possible for the material contained within the vial of "Kinetochore-associated protein DSN1 homolog (DSN1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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