Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47019(DAZ1 Antibody) at dilution 1/70. (Original magnification: 200))
Rabbit anti-Human DSC3 Polyclonal Antibody | anti-DSC3 antibody
DSC3 Antibody
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47019(DAZ1 Antibody) at dilution 1/70. (Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47019(DAZ1 Antibody) at dilution 1/70. (Original magnification: 200))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Uniprot Description
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Research Articles on DSC3
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Product Notes
The DSC3 dsc3 (Catalog #AAA9430031) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DSC3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DSC3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IF: 1: 25-100. Researchers should empirically determine the suitability of the DSC3 dsc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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