Western Blot (WB)
(Western Blot analysis of extracts of various cells, using DSC1 antibody.)
Rabbit DSC1 Polyclonal Antibody | anti-DSC1 antibody
DSC1 Polyclonal Antibody
Gene Names
DSC1; CDHF1; DG2/DG3
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
DSC1; Polyclonal Antibody; DSC1 Polyclonal Antibody; Desmocollin-1; Desmocollin 1; Desmocollin1; Cadherin family member 1; DG2/DG3; CDHF1; anti-DSC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
DSC1 polyclonal antibody detects endogenous levels of DSC1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
894
Applicable Applications for anti-DSC1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human DSC1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using DSC1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using DSC1 antibody.)
Related Product Information for anti-DSC1 antibody
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 100kDa
NCBI Official Full Name
desmocollin-1 isoform Dsc1a preproprotein
NCBI Official Synonym Full Names
desmocollin 1
NCBI Official Symbol
DSC1
NCBI Official Synonym Symbols
CDHF1; DG2/DG3
NCBI Protein Information
desmocollin-1
UniProt Protein Name
Desmocollin-1
Protein Family
UniProt Gene Name
DSC1
UniProt Synonym Gene Names
CDHF1
UniProt Entry Name
DSC1_HUMAN
NCBI Description
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]
Research Articles on DSC1
Similar Products
Product Notes
The DSC1 dsc1 (Catalog #AAA3008471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DSC1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DSC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the DSC1 dsc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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