Western Blot (WB)
(Western blot analysis of DRAGON (RGMB) Antibody (Center) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse DRAGON (RGMB) Polyclonal Antibody | anti-RGMB antibody
DRAGON (RGMB) Antibody (Center)
Western Blot (WB)
(Western blot analysis of DRAGON (RGMB) Antibody (Center) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of DRAGON (RGMB) Antibody (Center) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Metzger,M., Dev. Dyn. 234 (1), 169-175 (2005)
Xia,Y., Endocrinology 146 (8), 3614-3621 (2005)
NCBI and Uniprot Product Information
NCBI Description
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
Uniprot Description
RGMB: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth. Belongs to the repulsive guidance molecule (RGM) family.
Protein type: Membrane protein, GPI anchor; Cell adhesion; Transcription regulation
Chromosomal Location of Human Ortholog: 5q15
Cellular Component: anchored to plasma membrane; ER-Golgi intermediate compartment; plasma membrane; lipid raft
Molecular Function: identical protein binding; coreceptor activity
Biological Process: BMP signaling pathway; axon guidance; positive regulation of transcription, DNA-dependent; cell adhesion; signal transduction
Research Articles on RGMB
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Product Notes
The RGMB rgmb (Catalog #AAA9205235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 278-309. The DRAGON (RGMB) Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DRAGON (RGMB) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the RGMB rgmb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRAGON (RGMB), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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