Western Blot (WB)
(WB Suggested Anti-DPY30 antibody Titration: 1 ug/mLSample Type: Human Stomach Tumor)
Rabbit DPY30 Polyclonal Antibody | anti-DPY30 antibody
DPY30 Antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-DPY30 antibody Titration: 1 ug/mLSample Type: Human Stomach Tumor)
Western Blot (WB)
(WB Suggested Anti-DPY30 antibody Titration: 1 ug/mLSample Type: Human Stomach Tumor)
Target Description: DPY30 is a component of a Set1-like multiprotein histone methyltransferase complex.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016]
Uniprot Description
DPY30: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family.
Chromosomal Location of Human Ortholog: 2p22.3
Cellular Component: Golgi apparatus; histone methyltransferase complex; nucleoplasm; nucleus; trans-Golgi network
Molecular Function: histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; identical protein binding; protein binding; protein homodimerization activity
Biological Process: chromatin silencing at telomere; endosome transport; histone H3-K4 methylation
Research Articles on DPY30
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Product Notes
The DPY30 dpy30 (Catalog #AAA3214716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPY30 Antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's DPY30 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DPY30 dpy30 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PHSEYGLTDN VERIVENEKI NAEKSSKQKV DLQSLPTRAY LDQTVVPILL. It is sometimes possible for the material contained within the vial of "DPY30, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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