Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data (Fig-1: Expression analysis DPPA4. Anti-DPPA4 antibody (11-12042) was used at 1 ug/ml on Jurkat lysate.)

Rabbit DPPA4 Polyclonal Antibody | anti-DPPA4 antibody

Polyclonal Antibody to DPPA4

Gene Names
DPPA4; 2410091M23Rik
Reactivity
Human
Predicted: Mouse
Applications
Western Blot
Purity
Purified
Protein A Chromatography
Synonyms
DPPA4; Polyclonal Antibody; Polyclonal Antibody to DPPA4; Developmental pluripotency-associated protein 4; Antibody to DPPA4; Anti-DPPA4 Antibody; DPPA4 Antibody; anti-DPPA4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified
Protein A Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
304
Applicable Applications for anti-DPPA4 antibody
Western Blot (WB)
Application Notes
WB: 1-2 ug/ml
Immunogen Information
A partial length recombinant DPPA4 protein (amino acids 1-206) was used as the immunogen for this antibody.
Antigen
DPPA4
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Testing Data

(Fig-1: Expression analysis DPPA4. Anti-DPPA4 antibody (11-12042) was used at 1 ug/ml on Jurkat lysate.)

Testing Data (Fig-1: Expression analysis DPPA4. Anti-DPPA4 antibody (11-12042) was used at 1 ug/ml on Jurkat lysate.)
Related Product Information for anti-DPPA4 antibody
DPPA4 (Developmental pluripotency-associated 4) is a DNA binding SAP domain-containing protein. It is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. It is also mutated in some cancers. DPPA4 overexpression induces cell proliferation through genes related to regulation of G1/S transition. DPPA4 contains a functional HMG/POU cassette and behaves as a Sox2: Oct-3/4 target gene. Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis.
Product Categories/Family for anti-DPPA4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
33,541 Da
NCBI Official Full Name
Developmental pluripotency-associated protein 4
NCBI Official Synonym Full Names
developmental pluripotency associated 4
NCBI Official Symbol
DPPA4
NCBI Official Synonym Symbols
2410091M23Rik
NCBI Protein Information
developmental pluripotency-associated protein 4
UniProt Protein Name
Developmental pluripotency-associated protein 4
UniProt Gene Name
DPPA4

NCBI Description

This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

Uniprot Description

DPPA4: May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 3q13.13

Cellular Component: nucleoplasm

Molecular Function: protein binding

Biological Process: somatic stem cell maintenance

Research Articles on DPPA4

Similar Products

Product Notes

The DPPA4 dppa4 (Catalog #AAA668631) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to DPPA4 reacts with Human Predicted: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DPPA4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1-2 ug/ml. Researchers should empirically determine the suitability of the DPPA4 dppa4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DPPA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.