anti-Mouse DPPA2 Polyclonal Antibody | anti-DPPA2 antibody

DPPA2 Antibody

Cat. Num. AAA857344

• Gene Names: Dppa2; C80932; D19Mgi18; ECAT15-2; 2410088E07Rik
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: DPPA2; Polyclonal Antibody; DPPA2 Antibody; anti-DPPA2 antibody

• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of mouse DPPA2.
• Purity/Purification: Affinity purified
• Form/Format: 1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
• Sequence Length: 301

• Applicable Applications for anti-DPPA2 antibody: Western Blot (WB)
• Application Notes: WB: 1:2,000
• Preservative: 0.05% Sodium Azide.
• Cellular Localization: Cell Nudeus
• Positive Control: F9
• Preparation and Storage: Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.

Testing Data

(Fig: Western blot analysis on F9 using anti-DPPA2 polyclonal antibody)

Related Product Information for anti-DPPA2 antibody

DPPA2 (developmental pluripotency associated 2) is an embryo-cancer antigen that is coexpressed with cancer-testis antigens in non-small cell lung cancer. Dppa2 is closely linked SAP motif genes restricted to pluripotent cells and the germ line. It may play a role in maintaining cell pluripotentiality and in embryo preimplantation development.

References

1. Bortvin A., Eggan K., Skaletsky H., etc. "Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei."; Development 130:1673-1680(2003). 2. Du J., Lin G., Nie Z.Y., Lu G.X.; "Molecular cloning and characterization analysis of HPESCRG1, a novel gene expressed specifically in human embryonic stem cell."; Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:542-547(2004). 3. Carninci P., Kasukawa T., Katayama S., etc. Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J."The transcriptional landscape of the mammalian genome."; Science 309:1559-1563(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 58037335
• NCBI GeneID: 73703
• NCBI Accession #: NP_082891.1
• NCBI GenBank Nucleotide #: NM_028615.1
• UniProt Accession #: Q9CWH0
• Molecular Weight: 37kDa
• NCBI Official Full Name: developmental pluripotency-associated protein 2
• NCBI Official Synonym Full Names: developmental pluripotency associated 2
• NCBI Official Symbol: Dppa2
• NCBI Official Synonym Symbols: C80932; D19Mgi18; ECAT15-2; 2410088E07Rik
• NCBI Protein Information: developmental pluripotency-associated protein 2
• UniProt Protein Name: Developmental pluripotency-associated protein 2
• Protein Family: Developmental pluripotency-associated protein
• UniProt Gene Name: Dppa2
• UniProt Synonym Gene Names: Phsecrg1; ECAT15-2

Uniprot Description

Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.