Immunohistochemistry (IHC)
Rabbit Dopamine Receptor D4 Polyclonal Antibody | anti-Drd4 antibody
Dopamine D4 Receptor Antibody Affinity Purified
Dot Blot: 1:50,000
ELISA: 1:50,000
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Immunoprecipitation: 1:200
Western Blot: 1:1,000-1:1,5000
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Dopamine receptor mediated by G proteins which inhibit adenylyl cyclase. Modulates circadian rhtym of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells.
NCBI and Uniprot Product Information
Uniprot Description
DRD4: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Cellular Component: axon; cell cortex; cell soma; cytoplasm; dendrite; dendritic spine; integral to membrane; integral to plasma membrane; membrane; nerve terminal; plasma membrane; terminal button; vesicle membrane
Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine D2 receptor-like receptor activity; dopamine receptor activity; drug binding; G-protein coupled receptor activity; identical protein binding; SH3 domain binding; signal transducer activity
Biological Process: activation of MAPK activity; adult locomotory behavior; arachidonic acid secretion; associative learning; behavioral fear response; behavioral response to cocaine; dopamine receptor signaling pathway; dopamine receptor, adenylate cyclase inhibiting pathway; fear response; G-protein coupled receptor protein signaling pathway; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of protein secretion; olfactory learning; positive regulation of kinase activity; positive regulation of sodium:hydrogen antiporter activity; regulation of calcium-mediated signaling; regulation of circadian rhythm; regulation of dopamine metabolic process; regulation of inhibitory postsynaptic membrane potential; regulation of neurotransmitter secretion; regulation of synaptic transmission; response to amphetamine; rhythmic process; short-term memory; signal transduction; synaptic transmission, dopaminergic
Research Articles on Drd4
Similar Products
Product Notes
The Drd4 drd4 (Catalog #AAA540150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dopamine D4 Receptor Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Dopamine Receptor D4 can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). Confocal Microscopy||1:250 Dot Blot: 1:50,000 ELISA: 1:50,000 Immunocytochemistry: 1:250 Immunofluorescence: 1:250 Immunohistochemistry: 1:250 Immunoprecipitation: 1:200 Western Blot: 1:1,000-1:1,5000. Researchers should empirically determine the suitability of the Drd4 drd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dopamine Receptor D4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
